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Silicon Nanoparticle Delivery System for Controlled Release of Nucleic Acids Including siRNA and mRNA

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Summary

The USPTO published patent application US20260096997A1 assigned to SISAF LIMITED, filed November 6, 2025. The application covers a composition for controlled release of nucleic acids such as short interfering RNA (siRNA) or messenger RNA (mRNA), comprising silicon nanoparticles comprising at least 50% by weight silicon, at least one amino acid, and at least one lipid. The CPC classifications indicate primary focus on pharmaceutical preparations (A61K) and therapeutic uses including ophthalmological applications (A61P 27/02).

What changed

The USPTO published patent application US20260096997A1 for a silicon nanoparticle-based delivery system designed for controlled release of nucleic acids including siRNA and mRNA. The composition includes at least 50% silicon by weight, at least one amino acid, and at least one lipid. CPC classifications indicate relevance to pharmaceutical preparations (A61K 9/5115, A61K 9/127), nucleic acid therapeutics (A61K 31/713), and ophthalmological applications (A61P 27/02).

Affected parties in pharmaceutical manufacturing, biotechnology, and drug delivery technology sectors should monitor this patent application for potential future exclusivity claims in nucleic acid delivery systems. The application represents one of many entries in the expanding field of nanoparticle-based therapeutic delivery platforms targeting ocular and other therapeutic applications.

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  1. Monitor for updates

Archived snapshot

Apr 12, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

DELIVERY SYSTEM COMPRISING SILICON NANOPARTICLES

Application US20260096997A1 Kind: A1 Apr 09, 2026

Assignee

SISAF LIMITED

Inventors

Roghieh Suzanne SAFFIE-SIEBERT, Paulina Malgorzata BARAN-RACHWALSKA, Flavia Maria SUTERA, Nasrollah TORABI-POUR

Abstract

A composition for the controlled release of a nucleic acid such as short interfering RNA or messenger RNA, comprising silicon nanoparticles, at least one amino acid, and at least one lipid, wherein the silicon nanoparticles comprise at least 50% by weight silicon. Also related compositions and methods.

CPC Classifications

A61K 9/5115 A61K 9/0048 A61K 9/127 A61K 31/713 A61K 47/12 A61K 47/18 A61K 47/183 A61K 47/24 A61K 47/26 A61P 27/02

Filing Date

2025-11-06

Application No.

19381591

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260096997A1

Who this affects

Applies to
Drug manufacturers Healthcare providers Manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application RNA delivery system Nucleic acid therapeutics
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Regulatory Affairs
Topics
Pharmaceuticals Medical Devices Healthcare

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