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Shionogi Fused Ring GLP-1 Receptor Agonist Patent Application

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Summary

The USPTO published patent application US20260097037A1 by Shionogi & Co., Ltd. on April 9, 2026, covering fused ring compounds as GLP-1 receptor agonists for pharmaceutical use. The application was filed on September 21, 2023, under application number 19112403. The compounds are represented by formulas (I) and (II), with various substituents including phenyl groups and heterocyclic rings.

What changed

The USPTO published Shionogi & Co., Ltd.'s patent application covering fused ring compounds with GLP-1 receptor agonist activity, classified under CPC codes including C07D 471/04, C07D 471/18, and C07D 491/056. The compounds include formula (I) and (II) embodiments with substituents such as halogen, cyano, alkyl, and haloalkyl groups, with potential pharmaceutical applications.

For pharmaceutical companies and biotech firms developing GLP-1 based therapies, this published application establishes prior art as of September 2021. Competitors should conduct freedom-to-operate analyses to assess potential infringement risks. The patent claims covering fused ring GLP-1 agonists may affect product development strategies and patent filing timelines.

What to do next

  1. Monitor for patent issuance or examiner objections
  2. Review compound claims for freedom-to-operate analysis

Archived snapshot

Apr 11, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

FUSED RING COMPOUND HAVING GLP-1 RECEPTOR AGONIST EFFECT

Application US20260097037A1 Kind: A1 Apr 09, 2026

Assignee

Shionogi & Co., Ltd.

Inventors

Misato KITAMURA FUJIWARA, Yuji NISHIURA, Shomitsu MAENO, Hiroki KUSANO, Toshihiro WADA

Abstract

The present invention provides a compound represented by the following formula (I) or (II), or a pharmaceutically acceptable salt thereof. A compound represented by formula (I): whereinA1 is C(R1) or the like, R1 is a hydrogen atom or the like,R8 is a hydrogen atom or the like, B1 is CH or the like, R10 is cyano or the like, R3 is phenyl optionally substituted with substituent group F or the like,the substituent group F: halogen, cyano, alkyl, haloalkyl, alkyloxy, and haloalkyloxy,Q is a substituted or unsubstituted benzene ring or the like, R2 is substituted or unsubstituted alkyl or the like, and -L- is a group or the like shown below:

CPC Classifications

A61K 31/519 A61K 31/4184 A61K 31/4375 A61K 31/439 A61K 31/444 A61K 31/4725 A61K 31/4741 A61K 31/498 C07D 405/06 C07D 405/14 C07D 471/04 C07D 471/18 C07D 491/056 C07D 519/00

Filing Date

2023-09-21

Application No.

19112403

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260097037A1

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent filing Drug discovery
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Medical Devices

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