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IP and IP analogs dosage regimens for treatment of ectopic calcifications

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Summary

The USPTO granted patent US12594290B2 to Sanifit Therapeutics S.A. on April 7, 2026, covering compositions and dosage regimens of inositol phosphate compounds for treating ectopic calcifications, particularly calciphylaxis. The patent specifically claims daily doses of 6-9 mg/kg of myo-inositol hexaphosphate administered three times weekly for 1-8 months.

What changed

The USPTO granted Sanifit Therapeutics a new patent covering formulations and dosing protocols for inositol phosphate-based treatments of calciphylaxis and related calcification conditions. The patent provides Sanifit with exclusive market rights for these therapeutic applications in the US through the expiration date. Competitors developing similar ectopic calcification treatments must navigate around this patent protection or pursue licensing arrangements with Sanifit.

What to do next

  1. Monitor for patent portfolio implications
  2. Review licensing opportunities

Archived snapshot

Apr 7, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

IP and IP analogs dosage regimens for the treatment of ectopic calcifications

Grant US12594290B2 Kind: B2 Apr 07, 2026

Assignee

SANIFIT THERAPEUTICS S.A.

Inventors

Joan Perello Bestard, Carolina Salcedo Roca, Ana-Zeralda Canals Hamann

Abstract

The present disclosure related to compositions, methods, dosages, dosage regimens, articles of manufacture and kits for the treatment and/or prevention ectopic calcifications, and in particular cutaneous calcifications such as calciphylaxis calcifications comprising inositol phosphate, inositol phosphate analogs, inositol phosphate derivatives, or combinations thereof. In a particular aspect the disclosure provides a dosage regimen to treat calciphylaxis comprising the administration of 6 mg/kg to 9 mg/kg daily doses of myo-inositol hexaphosphate, three times a week, for at least 1 to 8 months.

CPC Classifications

A61K 31/7024 A61K 31/6615 A61K 31/7032 A61K 31/661 A61P 9/00 A61P 17/02 A61P 19/08

Filing Date

2025-02-27

Application No.

19065860

Claims

21

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Last updated

Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12594290B2

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent portfolio protection Drug formulation development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare

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