Changeflow GovPing Pharma & Drug Safety Ruxolitinib formulation for reduction of itch i...
Routine Notice Added Final

Ruxolitinib formulation for reduction of itch in atopic dermatitis

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Summary

USPTO granted Patent US12589096B2 to Incyte Corporation on March 31, 2026. The patent covers a topical 0.75% or 1.5% ruxolitinib cream formulation administered two times per day for reducing itch in patients with atopic dermatitis. The patent includes 20 claims and names Michael Kuligowski, Kang Sun, Michael Howell, May Grace E. Venturanza, and Jim Lee as inventors.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

USPTO granted Patent US12589096B2 to Incyte Corporation for a ruxolitinib cream formulation effective against atopic dermatitis itch. The patent covers topical compositions containing 0.75% or 1.5% ruxolitinib applied twice daily. Filing date was July 21, 2025, with Application No. 19274703 and 20 claims total.

This is a routine patent grant, not a regulatory action. No compliance deadlines, penalties, or required actions apply to third parties. Pharmaceutical companies and researchers should note this patent when developing competing itch treatments for atopic dermatitis to avoid infringement on the granted claims.

Archived snapshot

Mar 31, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Ruxolitinib formulation for reduction of itch in atopic dermatitis

Grant US12589096B2 Kind: B2 Mar 31, 2026

Assignee

Incyte Corporation

Inventors

Michael Kuligowski, Kang Sun, Michael Howell, May Grace E. Venturanza, Jim Lee

Abstract

This disclosure relates to methods of reducing itch in patients with atopic dermatitis and treating patients with atopic dermatitis by administering a topical 0.75% or 1.5% ruxolitinib cream two times per day.

CPC Classifications

A61K 31/519 A61K 31/4155 A61K 9/0014 A61K 47/14 A61K 9/06 A61K 9/107 A61P 17/00

Filing Date

2025-07-21

Application No.

19274703

Claims

20

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Last updated

Classification

Agency
USPTO
Published
March 31st, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12589096B2

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Pharmaceutical Formulation Patents
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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