Ruxolitinib formulation for reduction of itch in atopic dermatitis
Summary
USPTO granted Patent US12589096B2 to Incyte Corporation on March 31, 2026. The patent covers a topical 0.75% or 1.5% ruxolitinib cream formulation administered two times per day for reducing itch in patients with atopic dermatitis. The patent includes 20 claims and names Michael Kuligowski, Kang Sun, Michael Howell, May Grace E. Venturanza, and Jim Lee as inventors.
What changed
USPTO granted Patent US12589096B2 to Incyte Corporation for a ruxolitinib cream formulation effective against atopic dermatitis itch. The patent covers topical compositions containing 0.75% or 1.5% ruxolitinib applied twice daily. Filing date was July 21, 2025, with Application No. 19274703 and 20 claims total.
This is a routine patent grant, not a regulatory action. No compliance deadlines, penalties, or required actions apply to third parties. Pharmaceutical companies and researchers should note this patent when developing competing itch treatments for atopic dermatitis to avoid infringement on the granted claims.
Archived snapshot
Mar 31, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Ruxolitinib formulation for reduction of itch in atopic dermatitis
Grant US12589096B2 Kind: B2 Mar 31, 2026
Assignee
Incyte Corporation
Inventors
Michael Kuligowski, Kang Sun, Michael Howell, May Grace E. Venturanza, Jim Lee
Abstract
This disclosure relates to methods of reducing itch in patients with atopic dermatitis and treating patients with atopic dermatitis by administering a topical 0.75% or 1.5% ruxolitinib cream two times per day.
CPC Classifications
A61K 31/519 A61K 31/4155 A61K 9/0014 A61K 47/14 A61K 9/06 A61K 9/107 A61P 17/00
Filing Date
2025-07-21
Application No.
19274703
Claims
20
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Source
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