SC Board of Pharmacy: Revised Vaccine Administration Protocol
Summary
The South Carolina Board of Pharmacy has revised its protocol for vaccine administration by pharmacists, effective September 17, 2025. The primary change allows pharmacists, interns, and technicians to administer FDA-approved COVID-19 vaccines without a practitioner's order, following specific professional recommendations.
What changed
The South Carolina Board of Medical Examiners has approved revisions to the SC Protocol for Administration of Vaccines by Pharmacists, effective September 17, 2025. The key update permits pharmacists, pharmacy interns, and eligible pharmacy technicians to administer FDA-approved COVID-19 vaccines without a licensed practitioner's order, provided the administration aligns with recommendations from recognized bodies such as ACIP, AAP, AAFP, or ACOG.
Regulated entities, specifically pharmacies and their personnel in South Carolina, should review the updated protocol to ensure compliance. This change impacts the scope of practice for pharmacists and technicians regarding COVID-19 vaccinations, potentially increasing accessibility. No specific compliance deadline is mentioned beyond the effective date of the protocol.
What to do next
- Review the revised SC Protocol for Administration of Vaccines by Pharmacists.
- Ensure pharmacists, interns, and technicians are aware of and comply with the updated guidelines for administering COVID-19 vaccines without a practitioner's order.
Source document (simplified)
Revised Protocol for Administration of Vaccines by Pharmacists
The South Carolina Board of Medical Examiners has approved revisions to the SC Protocol for Administration of Vaccines by Pharmacists, effective September 17, 2025. These revisions follow recommendations made by the Joint Pharmacist Administered Vaccines Committee on September 15, 2025.
While several updates were made to the Protocol, the primary change authorizes pharmacists, pharmacy interns and eligible pharmacy technicians to administer FDA-approved COVID-19 vaccines without a licensed practitioner’s order in accordance with recommendations from:
- the Advisory Committee on Immunizations Practices (ACIP),
- the American Academy of Pediatrics (AAP),
- the American Academy of Family Physicians (AAFP), OR
- the American College of Obstetricians and Gynecologists (ACOG). You may review the revised protocol here.
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