Changeflow GovPing Pharma & Drug Safety RAGE Antibodies Patent Granted SUNY Apr 14
Routine Rule Added Final

RAGE Antibodies Patent Granted SUNY Apr 14

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Summary

USPTO granted Patent US12600778B2 to The Research Foundation for The State University of New York for antibodies specific to the heparan sulfate binding site of Receptor for Advanced Glycation Endproducts (RAGE). The patent includes methods for treating conditions involving RAGE through antibody administration, with 4 claims allowed.

What changed

USPTO granted Patent US12600778B2 to The Research Foundation for The State University of New York on April 14, 2026. The patent covers antibodies specific for the heparan sulfate binding site of Receptor for Advanced Glycation Endproducts (RAGE), along with methods for treating conditions in which RAGE is involved through antibody administration. The patent application was filed November 2, 2020, under application number 17772853.

For biotech and pharmaceutical companies, this patent establishes intellectual property protection for RAGE-targeted antibody therapeutics. The 4-claim patent provides the assignee exclusive rights in the US for approximately 20 years from filing. Research institutions and companies developing RAGE-related therapies should review this patent to assess potential freedom-to-operate implications or licensing opportunities.

What to do next

  1. Monitor patent maintenance requirements
  2. Ensure proper assignment documentation

Archived snapshot

Apr 14, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Rage antibodies, fragments and uses thereof

Grant US12600778B2 Kind: B2 Apr 14, 2026

Assignee

The Research Foundation for The State University of New York

Inventors

Ding Xu, Jeffrey Esko, Miaomiao Li

Abstract

Provided are antibodies specific for the heparan sulfate binding site of Receptor for Advanced Glycation Endproducts (RAGE). Also provided are methods for treating of conditions in which RAGE is involved comprising administration of the antibodies to an individual in need of treatment.

CPC Classifications

C07K 16/2803 C07K 2317/565 C07K 2317/73 C07K 2317/92 C07K 2317/24 C07K 2317/33 C07K 2317/76 A61K 47/6811 A61K 2039/505 A61P 1/16 A61P 19/10 A61P 35/00

Filing Date

2020-11-02

Application No.

17772853

Claims

4

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Last updated

Classification

Agency
USPTO
Published
April 14th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12600778B2

Who this affects

Applies to
Pharmaceutical companies Medical device makers Research institutions
Industry sector
3254.1 Biotechnology
Activity scope
Patent granting Biotechnology research Therapeutic antibody development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Medical Devices

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