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Quinoline Compounds as Cyclin Dependent Kinase Inhibitors

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Published March 11th, 2026
Detected March 26th, 2026
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Summary

The European Patent Office has published patent application EP4514791A1, detailing substituted 6-(pyrimidin-4-yl) quinoline compounds as cyclin dependent kinase inhibitors. The application was published on March 11, 2026, and lists BeOne Medicines I GmbH as the applicant.

What changed

The European Patent Office (EPO) has published a patent application, EP4514791A1, for substituted 6-(pyrimidin-4-yl) quinoline compounds that act as cyclin-dependent kinase (CDK) inhibitors. This publication indicates a new potential therapeutic agent for conditions like cancer, as indicated by the A61P 35/00 classification (treatment of cancer).

While this is a patent publication and not a regulatory rule with direct compliance obligations for most entities, it is significant for pharmaceutical and biotechnology companies involved in drug development. Companies operating in this space should be aware of this patent filing as it may impact their own research and development pipelines or intellectual property strategies. The designated states indicate broad European coverage for this patent application.

Source document (simplified)

← EPO Patent Bulletin

SUBSTITUTED 6- (PYRIMIDIN-4-YL) QUINOLINE COMPOUNDS AS CYCLIN DEPENDENT KINASE INHIBITORS

Publication EP4514791A1 Kind: A1 Mar 11, 2026

Applicants

BeOne Medicines I GmbH

Inventors

LI, Jing, XU, Wenqing, WANG, Zhiwei

IPC Classifications

C07D 405/14 20060101AFI20260203BHEP C07D 405/04 20060101ALI20260203BHEP C07D 401/04 20060101ALI20260203BHEP C07D 401/14 20060101ALI20260203BHEP A61K 31/5377 20060101ALI20260203BHEP A61P 35/00 20060101ALI20260203BHEP C07D 498/08 20060101ALI20260203BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Classification

Agency
EPO
Published
March 11th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
EP4514791A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Drug Development Intellectual Property
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Drug Development Intellectual Property

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