Polyglutamated Antifolates and Uses Thereof (EP3496757A1)
Summary
The European Patent Office published patent application EP3496757A1 for polyglutamated antifolates and their therapeutic uses, filed by L.E.A.F Holdings Group LLC. The patent covers compositions for treating cancer and inflammatory conditions. The application was published April 8, 2026, designating 36 European states including Germany, France, the United Kingdom, Italy, Spain, and other EU member states. No compliance deadlines or penalties are specified.
What changed
The EPO published patent application EP3496757A1 for polyglutamated antifolates and their uses in treating cancer and inflammatory diseases. The application covers pharmaceutical compositions containing antifolate compounds, including claims related to drug formulations and therapeutic methods. Inventors include Clet Niyikiza and Victor Mandla Moyo.
Affected parties in designated EU states should monitor the progression of this patent application through grant proceedings. Pharmaceutical companies developing antifolate-based therapeutics may need to evaluate freedom-to-operate considerations. Research institutions conducting related work should assess potential licensing needs if the patent proceeds to grant.
What to do next
- Monitor for patent grant proceedings
- Review licensing opportunities if operating in designated EU states
Archived snapshot
Apr 16, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
POLYGLUTAMATED ANTIFOLATES AND USES THEREOF
Publication EP3496757A1 Kind: A1 Apr 08, 2026
Applicants
L.E.A.F Holdings Group LLC
Inventors
NIYIKIZA, Clet, MOYO, Victor, Mandla
IPC Classifications
A61K 9/12 20060101AFI20260302BHEP A61K 45/06 20060101ALI20260302BHEP A61P 35/00 20060101ALI20260302BHEP A61K 31/517 20060101ALI20260302BHEP A61K 31/519 20060101ALI20260302BHEP A61K 47/64 20170101ALI20260302BHEP A61P 19/02 20060101ALI20260302BHEP C07K 16/28 20060101ALI20260302BHEP A61K 47/68 20170101ALI20260302BHEP A61K 47/69 20170101ALI20260302BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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Source
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