Bipartite molecules treating neurodegenerative diseases
Summary
USPTO granted Patent US12590130B2 to Academia Sinica for bipartite molecules comprising a peptide affinity moiety and charged moieties for treating neurodegenerative diseases associated with abnormal protein aggregates. The patent contains 6 claims and was granted March 31, 2026, with original filing date November 27, 2020. No compliance deadlines are associated with this patent grant.
What changed
USPTO granted Patent US12590130B2 to Academia Sinica (Taiwan) covering bipartite molecules with peptide affinity and charged moieties designed to reduce abnormal protein aggregate formation for treating neurodegenerative diseases. The patent names 8 inventors and includes 6 claims. This is a standard patent grant notification informing the public of newly issued patent rights.
Pharmaceutical companies and biotechnology firms developing treatments for neurodegenerative diseases should review this patent to assess potential licensing needs orFreedom-to-operate implications for competing therapeutic approaches. Drug manufacturers conducting research in this space may need to consider patent clearance before commercializing related products.
Archived snapshot
Mar 31, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Bipartite molecules and uses thereof in treating diseases associated with abnormal protein aggregates
Grant US12590130B2 Kind: B2 Mar 31, 2026
Assignee
Academia Sinica
Inventors
Benjamin Pang-Hsien Tu, Rita Py Chen, Joseph Jen-Tse Huang, Yijuang Chern, Yu-Song Jang, Xiang-Me Lai, Tai-Yan Liao, Te-Hsien Kung
Abstract
Bipartite molecules comprising a peptide affinity moiety and at least one charged moiety and uses thereof in reducing formation of abnormal protein aggregate and treating diseases associated with such abnormal protein aggregate, including neurodegenerative disease characterized by formation of protein aggregates.
CPC Classifications
C07K 14/4711 C07K 14/4703 C07K 2319/00 A61K 38/00
Filing Date
2020-11-27
Application No.
17105858
Claims
6
Named provisions
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Source
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