USPTO Patent Grant: Oxetane Derivative Synthesis Method by Microreactor
Summary
The USPTO has granted a patent (US12583830B2) for a microreactor-based synthesis method for oxetane derivatives. The patent, assigned to Changzhou Tronly Advanced Electronic Materials Co., Ltd., details a process that improves efficiency, yield, and safety compared to traditional methods.
What changed
The United States Patent and Trademark Office (USPTO) has issued a patent (US12583830B2) for a novel synthesis method of oxetane derivatives using a microreactor. The patent, filed on March 16, 2021, and granted on March 24, 2026, describes a process involving etherification reactions within a microreactor, utilizing specific raw materials, catalysts, and alkalis to produce the desired oxetane derivative. The assignee is Changzhou Tronly Advanced Electronic Materials Co., Ltd.
This patent grant signifies a new intellectual property right for a specific chemical synthesis process. While not imposing direct compliance obligations on other entities, it may influence research and development strategies in the pharmaceutical and chemical manufacturing sectors. Companies operating in this space should be aware of this patented technology to avoid potential infringement issues and to identify opportunities for licensing or alternative process development. The patent highlights improvements in reaction time, production efficiency, yield, continuity, automation, and safety due to the use of microreactor technology.
What to do next
- Review patent US12583830B2 for potential impact on existing or planned synthesis processes.
- Consult with legal counsel regarding potential licensing or infringement risks related to oxetane derivative synthesis.
Archived snapshot
Mar 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Synthesis method for synthesizing oxetane derivative by microreactor
Grant US12583830B2 Kind: B2 Mar 24, 2026
Assignee
Changzhou Tronly Advanced Electronic Materials Co., Ltd.
Inventors
Xiaochun Qian
Abstract
The invention provides a synthesis method for synthesizing an oxetane derivative by a microreactor. The synthesis method comprises: delivering 3-ethyl-3-hydroxymethyloxetane, a raw material Ha, a catalyst, and an alkali into a microreactor, and performing an etherification reaction so as to obtain an etherification product system, the raw material Ha having a general formula of R-(X)n, and X being a halogen; and separating the etherification product system so as to obtain the oxetane derivative. The microreactor is used for greatly improving the mass and heat transfer properties of the reaction system, reducing the reaction time, improving the production efficiency, increasing the yield of the product, achieving the continuity and automation of the process, and improving the safety of the process. In addition, the reaction device required by the described synthesis process requires has a small size, requires less manpower and has high safety.
CPC Classifications
C07D 305/06
Filing Date
2021-03-16
Application No.
17913671
Claims
11
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