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USPTO Patent Grant: Methods Treating Disorders Using CSFIR Inhibitors

Favicon for changeflow.com USPTO Patent Grants - Therapeutics (A61P)
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Summary

The USPTO has granted patent US12582655B2 to Deciphera Pharmaceuticals, LLC for methods of treating cancers and other tumors using CSFIR inhibitors. The patent covers methods related to the proliferation, depletion, or repolarization of tumor-associated macrophages (TAMs).

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

The United States Patent and Trademark Office (USPTO) has granted patent US12582655B2, titled 'Methods of treating disorders using CSFIR inhibitors,' to Deciphera Pharmaceuticals, LLC. This patent covers specific methods for treating various cancers and tumors by targeting tumor-associated macrophages (TAMs), including conditions such as tenosynovial giant cell tumor (TGCT) and diffuse-type tenosynovial giant cell tumor (DTGCT).

This patent grant is primarily of interest to pharmaceutical and drug manufacturing companies involved in oncology research and development. While it does not impose direct compliance obligations on other entities, it signifies intellectual property protection for specific therapeutic approaches. Companies operating in this space should be aware of this granted patent as it may impact their freedom to operate or inform their own R&D strategies.

Archived snapshot

Mar 24, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Methods of treating disorders using CSFIR inhibitors

Grant US12582655B2 Kind: B2 Mar 24, 2026

Assignee

Deciphera Pharmaceuticals, LLC

Inventors

Daniel L. Flynn, Bryan D. Smith, Rodrigo Ruiz Soto, Keisuke Kuida

Abstract

Described herein are methods of treating cancers and other tumors related to the decreased proliferation, the depletion, or the repolarization of tumor-associated macrophages (TAMs) and treatment of associated disorders, including tenosynovial giant cell tumor (TGCT) and diffuse-type tenosynovial giant cell tumor (DTGCT).

CPC Classifications

A61K 31/505 A61P 35/00 A61P 35/02

Filing Date

2025-10-21

Application No.

19364654

Claims

29

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Last updated

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12582655B2

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Cancer Treatment
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Cancer Treatment Drug Development

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