USPTO Patent Grant: Methods Treating Disorders Using CSFIR Inhibitors
Summary
The USPTO has granted patent US12582655B2 to Deciphera Pharmaceuticals, LLC for methods of treating cancers and other tumors using CSFIR inhibitors. The patent covers methods related to the proliferation, depletion, or repolarization of tumor-associated macrophages (TAMs).
What changed
The United States Patent and Trademark Office (USPTO) has granted patent US12582655B2, titled 'Methods of treating disorders using CSFIR inhibitors,' to Deciphera Pharmaceuticals, LLC. This patent covers specific methods for treating various cancers and tumors by targeting tumor-associated macrophages (TAMs), including conditions such as tenosynovial giant cell tumor (TGCT) and diffuse-type tenosynovial giant cell tumor (DTGCT).
This patent grant is primarily of interest to pharmaceutical and drug manufacturing companies involved in oncology research and development. While it does not impose direct compliance obligations on other entities, it signifies intellectual property protection for specific therapeutic approaches. Companies operating in this space should be aware of this granted patent as it may impact their freedom to operate or inform their own R&D strategies.
Archived snapshot
Mar 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Methods of treating disorders using CSFIR inhibitors
Grant US12582655B2 Kind: B2 Mar 24, 2026
Assignee
Deciphera Pharmaceuticals, LLC
Inventors
Daniel L. Flynn, Bryan D. Smith, Rodrigo Ruiz Soto, Keisuke Kuida
Abstract
Described herein are methods of treating cancers and other tumors related to the decreased proliferation, the depletion, or the repolarization of tumor-associated macrophages (TAMs) and treatment of associated disorders, including tenosynovial giant cell tumor (TGCT) and diffuse-type tenosynovial giant cell tumor (DTGCT).
CPC Classifications
A61K 31/505 A61P 35/00 A61P 35/02
Filing Date
2025-10-21
Application No.
19364654
Claims
29
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