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LAG-3 Antibody Combination Therapies - Patent US12600777B2

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Summary

The USPTO granted patent US12600777B2 to Novartis AG covering combination therapies comprising antibody molecules that specifically bind to LAG-3. The patent contains seven claims and relates to methods for treating, preventing, and/or diagnosing cancerous or infectious disorders. This represents a grant of exclusive intellectual property rights to Novartis AG for the therapeutic application of LAG-3 antibody combinations.

What changed

The USPTO issued patent US12600777B2 to Novartis AG on April 14, 2026, granting exclusive intellectual property rights for combination therapies comprising antibody molecules that specifically bind to LAG-3. The patent includes seven claims covering methods of treating cancerous or infectious disorders using these combination therapies. Inventors include Glenn Dranoff, Frederic Triebel, and others.\n\nFor pharmaceutical companies and biotechnology firms developing immunotherapy treatments, this patent establishes enforceable IP rights that may affect freedom-to-operate assessments for LAG-3 targeted combination therapies. Companies researching similar combination approaches should evaluate potential licensing requirements or design-around strategies.

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Archived snapshot

Apr 14, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Combination therapies comprising antibody molecules to LAG-3

Grant US12600777B2 Kind: B2 Apr 14, 2026

Assignee

Novartis AG

Inventors

Glenn Dranoff, Frederic Triebel, Chrystelle Brignone, Walter A. Blattler, Jennifer Marie Mataraza, Catherine Ann Sabatos-Peyton, Hwai Wen Chang, Gerhard Johann Frey

Abstract

Combination therapies comprising antibody molecules that specifically bind to LAG-3 are disclosed. The combination therapies can be used to treat, prevent and/or diagnose cancerous or infectious disorders.

CPC Classifications

C07K 16/2803 C07K 2317/24 C07K 2317/76 C07K 2317/92 A61P 35/00

Filing Date

2021-09-30

Application No.

17491420

Claims

7

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Last updated

Classification

Agency
USPTO
Published
April 14th, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12600777B2

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent granting IP licensing
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare

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