KRAS Inhibitor Heterocyclic Compounds for Cancer Treatment
Summary
USPTO published patent application US20260092075A1 for KRAS inhibitor heterocyclic compounds designed for cancer treatment. The application covers novel chemical compounds of specified formula, their pharmaceutical salts, and methods of using these compounds for treating cancer patients. Filing date was September 30, 2025.
What changed
USPTO published patent application US20260092075A1 disclosing KRAS inhibitor heterocyclic compounds for cancer treatment. The application claims compounds with specific structural formulas (A, B, R1, R2, R3a, R3b, Z1, Z2, Z3 as described), their pharmaceutically acceptable salts, and associated treatment methods. CPC classifications indicate primary focus on C07D chemistry (heterocyclic compounds), A61K pharmaceutical compositions, and A61P antineoplastic agents.
This is a patent application publication with no regulatory compliance requirements. Pharmaceutical and biotech companies researching KRAS oncological targets may review the claimed compound structures to assess freedom-to-operate considerations or identify potential licensing opportunities. No immediate action is required by regulated entities.
Archived snapshot
Apr 2, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
KRAS INHIBITORS
Application US20260092075A1 Kind: A1 Apr 02, 2026
Inventors
Adedoyin David ABRAHAM, Sean ARONOW, Desta BUME, Xiaohong CHEN, Sonia Maria GUTIERREZ SANFELICIANO, Timothy Scott KERCHER, Wenceslao LUMERAS AMADOR, Ramkumar RAJAMANI, Isabel ROJO GARCIA, William Rush SCAGGS, Shane WALLS
Abstract
Provided herein are compounds of the formula: wherein A, B, R1, R2, R3a, R3b, Z1, Z2, and Z3 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients with cancer.
CPC Classifications
C07D 519/00 A61K 31/4741 A61K 31/5025 A61K 31/519 A61K 31/5377 A61K 31/5383 A61K 45/06 A61P 35/00 C07B 59/002 C07D 491/048
Filing Date
2025-09-30
Application No.
19344841
Named provisions
Related changes
Get daily alerts for USPTO Patent Applications - Organic Chemistry (C07D)
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from USPTO.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when USPTO Patent Applications - Organic Chemistry (C07D) publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.