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KRAS Inhibitor Heterocyclic Compounds for Cancer Treatment

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Summary

USPTO published patent application US20260092075A1 for KRAS inhibitor heterocyclic compounds designed for cancer treatment. The application covers novel chemical compounds of specified formula, their pharmaceutical salts, and methods of using these compounds for treating cancer patients. Filing date was September 30, 2025.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

USPTO published patent application US20260092075A1 disclosing KRAS inhibitor heterocyclic compounds for cancer treatment. The application claims compounds with specific structural formulas (A, B, R1, R2, R3a, R3b, Z1, Z2, Z3 as described), their pharmaceutically acceptable salts, and associated treatment methods. CPC classifications indicate primary focus on C07D chemistry (heterocyclic compounds), A61K pharmaceutical compositions, and A61P antineoplastic agents.

This is a patent application publication with no regulatory compliance requirements. Pharmaceutical and biotech companies researching KRAS oncological targets may review the claimed compound structures to assess freedom-to-operate considerations or identify potential licensing opportunities. No immediate action is required by regulated entities.

Archived snapshot

Apr 2, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

KRAS INHIBITORS

Application US20260092075A1 Kind: A1 Apr 02, 2026

Inventors

Adedoyin David ABRAHAM, Sean ARONOW, Desta BUME, Xiaohong CHEN, Sonia Maria GUTIERREZ SANFELICIANO, Timothy Scott KERCHER, Wenceslao LUMERAS AMADOR, Ramkumar RAJAMANI, Isabel ROJO GARCIA, William Rush SCAGGS, Shane WALLS

Abstract

Provided herein are compounds of the formula: wherein A, B, R1, R2, R3a, R3b, Z1, Z2, and Z3 are as described herein, pharmaceutically acceptable salts thereof, and methods of using these compounds and pharmaceutically acceptable salts thereof for treating patients with cancer.

CPC Classifications

C07D 519/00 A61K 31/4741 A61K 31/5025 A61K 31/519 A61K 31/5377 A61K 31/5383 A61K 45/06 A61P 35/00 C07B 59/002 C07D 491/048

Filing Date

2025-09-30

Application No.

19344841

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Named provisions

Abstract CPC Classifications Inventors

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Last updated

Classification

Agency
USPTO
Published
April 2nd, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260092075A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers Healthcare providers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent Filings Pharmaceutical Research
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Topics
Intellectual Property Healthcare Cancer Treatment

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