Ionizable Lipidoid Compositions and Therapeutic Uses Thereof
Summary
Ionizable Lipidoid Compounds for Therapeutic Agent Delivery
What changed
The USPTO published patent application US20260098014A1 covering ionizable lipidoid compounds of formula (I) and nanoparticle compositions for delivering therapeutic agents. The application includes pharmaceutical compositions comprising these lipidoid delivery systems.
Pharmaceutical and biotechnology companies developing drug delivery technologies should review this patent application for potential freedom-to-operate considerations. The broad claims to lipidoid-based therapeutic delivery systems may affect product development strategies for lipid nanoparticle and nucleic acid delivery platforms.
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Apr 9, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
IONIZABLE LIPIDOID COMPOSITIONS AND THERAPEUTIC USES THEREOF
Application US20260098014A1 Kind: A1 Apr 09, 2026
Inventors
Srinivas Abbina, Chelsea RamEl Martinez, Vandan Paresh Jakharia, Timothy Ray Blake, Ulugbek Barotov
Abstract
Disclosed are lipidoid compounds having the structure of formula (I): or a salt thereof, wherein the groups are as defined in the application. Also disclosed are nanoparticle compositions comprising a lipidoid of the invention that are capable of delivering a therapeutic agent. The application also discloses pharmaceutical compositions comprising a lipidoid composition of the invention.
CPC Classifications
C07D 233/36 A61K 9/5123 A61K 48/0041 C07C 229/24 C07D 205/04 C07D 207/09 C07D 211/26 C07D 233/61 C07D 239/10 C07D 295/13 C07D 317/38 C07F 9/65742 C07C 2601/08
Filing Date
2025-10-08
Application No.
19352724
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