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Ion Pair Liquid Crystal Formulations for Long-Acting Injectables of Poorly Soluble Drugs

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Summary

USPTO published patent application US20260097044A1 by FORDOZ PHARMA Corp. disclosing ion pair liquid crystal formulations designed to solubilize poorly soluble drugs and enable controlled release via parenteral administration. The application covers ion pairs including Meloxicam-Dodecylamine, Sulfadiazine-Dodecylamine, Methotrexate-Dodecylamine, Levothyroxine-Dodecylamine, Meloxicam-Tridodecylamine, and Meloxicam-Bupivacaine incorporated into liquid crystal vehicles.

What changed

USPTO published patent application US20260097044A1 by FORDOZ PHARMA Corp. disclosing ion pair liquid crystal formulations designed to solubilize poorly soluble drugs and enable controlled release via parenteral administration. The application specifically covers ion pairs including Meloxicam-Dodecylamine, Sulfadiazine-Dodecylamine, Methotrexate-Dodecylamine, Levothyroxine-Dodecylamine, Meloxicam-Tridodecylamine, and Meloxicam-Bupivacaine incorporated into liquid crystal vehicles for injectable drug delivery.

Pharmaceutical companies and drug developers should monitor this application as it indicates potential competitive activity in poorly soluble drug formulation using liquid crystal technology. Competitors developing long-acting injectable products may need to assess freedom-to-operate implications for their own formulation programs.

What to do next

  1. Monitor competitor patent activity in long-acting injectable formulation space
  2. Review internal R&D programs for freedom-to-operate implications
  3. Ensure trade secret protections for proprietary formulation technologies

Archived snapshot

Apr 10, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

ION PAIR LIQUID CRYSTAL FORMULATIONS FOR LONG-ACTING INJECTABLES OF POORLY SOLUBLE DRUGS

Application US20260097044A1 Kind: A1 Apr 09, 2026

Assignee

FORDOZ PHARMA Corp.

Inventors

Yuan Chen, Sydney Ugwu, Yiwen Wang, James He

Abstract

This application discloses a method to solubilize poorly soluble drugs in a liquid crystal vehicle for long-acting injectables. Poorly soluble acidic drugs-hydrophobic basic compounds ion pairs are incorporated into liquid crystal vehicles to solubilize and slowly release the drug after parenteral administration. Ion pairs such as Meloxicam-Dodecylamine, Sulfadiazine-Dodecylamine, Methotrexate-Dodecylamine, Levothyroxine-Dodecylamine, Meloxicam-Tridodecylamine, and Meloxicam-Bupivacaine are incorporated into liquid crystal vehicles to solubilize and control release the drugs.

CPC Classifications

A61K 31/5415 A61K 31/198 A61K 31/445 A61K 31/505 A61K 31/519 A61K 47/10 A61K 47/14 A61K 47/20 A61K 47/22 A61K 47/24

Filing Date

2025-09-24

Application No.

19338302

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Named provisions

Abstract Ion Pair Formulations Liquid Crystal Vehicles Parenteral Administration

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260097044A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application Drug formulation development
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Medical Devices

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