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Improved Process for Preparing Risdiplam and Its Intermediates

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Summary

The USPTO published patent application US20260098048A1 for an improved chemical synthesis process for Risdiplam, a pharmaceutical compound used to treat spinal muscular atrophy. The application also discloses novel intermediates involved in the preparation process. This is a routine patent publication that does not create immediate compliance obligations.

What changed

The USPTO published patent application US20260098048A1 disclosing an improved process for synthesizing Risdiplam and its novel intermediates. This represents a routine patent publication covering a pharmaceutical manufacturing process that does not impose compliance obligations on third parties.

Pharmaceutical manufacturers and researchers in organic chemistry should monitor the application's progression through examination, as the granted patent could affect Risdiplam manufacturing processes, competitive positioning, and licensing opportunities in the SMA treatment market.

What to do next

  1. Monitor for patent grant and final claim scope
  2. Evaluate licensing or competitive implications

Archived snapshot

Apr 10, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

IMPROVED PROCESS FOR THE PREPARATION OF RISDIPLAM AND ITS INTERMEDIATES

Application US20260098048A1 Kind: A1 Apr 09, 2026

Inventors

Sathaiah KANDULA, Rama Krishna YADLAPALLI, Bulli Babi VIPPARLA, Sathish THUMATI, Sreenivas NAGAPURI, Srikanth PARAKALA, Sashikanth SUTHRAPU, Ramesh DANDALA, Pulla Reddy MUDDASANI, Venkaiah Chowdary NANNAPANENI

Abstract

The present invention relates to an improved process for the preparation of Risdiplam compound of Formula-I. The present invention also relates to novel intermediates of Risdiplam compound of Formula-I and process for the preparation of the same.

CPC Classifications

C07D 519/00 C07D 241/38

Filing Date

2023-09-25

Application No.

19113864

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US20260098048A1

Who this affects

Applies to
Pharmaceutical companies Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Patent application Chemical synthesis
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals

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