Root-Mediated Uptake of Guide RNA for Genomic Editing of a Plant
Summary
USPTO published patent application US20260098274A1 by Inari Agriculture Technology disclosing methods for editing plant genomes by delivering guide RNA to plant roots for CRISPR-Cas editing in meristems. Inventors include Aran McCay, Michael Lee Nuccio, and Palak Kathiria. The filing date was March 7, 2024.
What changed
USPTO published patent application US20260098274A1 by Inari Agriculture Technology disclosing methods for editing plant genomes by delivering guide RNA to plant roots for uptake and transport to meristem cells for CRISPR-Cas editing.
The publication does not create compliance obligations but may be relevant for entities in agricultural biotechnology and crop development seeking to understand the intellectual property landscape around CRISPR guide RNA delivery methods in plants.
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Archived snapshot
Apr 13, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
ROOT-MEDIATED UPTAKE OF GUIDE RNA FOR GENOMIC EDITING OF A PLANT
Application US20260098274A1 Kind: A1 Apr 09, 2026
Assignee
Inari Agriculture Technology, Inc.
Inventors
Aran MCCAY, Michael Lee NUCCIO, Palak KATHIRIA
Abstract
The present disclosure provides methods for editing a genomic target in a meristem of a plant that expresses Cas editing reagents by delivering to a plant root a guide RNA for the Cas nuclease. Various methods of delivering the guide RNA are provided. Plants edited using the methods are also provided.
CPC Classifications
C12N 15/8229 C12N 9/226 C12N 15/111 C12N 15/8205 C12N 2310/20
Filing Date
2024-03-07
Application No.
19163344
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