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Foghorn Therapeutics Patent for Heterocyclic Compounds Treating BAF Disorders

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Summary

The USPTO granted patent US12590079B2 to Foghorn Therapeutics Inc. on March 31, 2026, covering heterocyclic compounds useful for treating BAF complex-related disorders. The patent names inventors Sabine K. Ruppel, Zhaoxia Yang, and Jason T. Lowe, with claims encompassing 20 compound variations classified under CPC codes C07D 401/14, C07D 471/04, C07D 471/10, and C07D 487/04.

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What changed

The USPTO issued Patent No. US12590079B2 to Foghorn Therapeutics Inc. on March 31, 2026, granting exclusive rights to heterocyclic compounds and their uses for treating BAF complex-related disorders. The patent application (No. 17631791) was filed on July 31, 2020, and the granted patent contains 20 claims covering the compound compositions and methods of treatment. The CPC classifications indicate applications in cancer treatment (A61P 35/00) alongside heterocyclic chemistry classifications.

This patent grant establishes Foghorn Therapeutics' intellectual property rights in this therapeutic area, potentially affecting freedom-to-operate considerations for other companies developing similar compounds for BAF complex-related disorders. No immediate compliance actions are required by regulated entities; however, companies in the oncology or epigenetic therapy space should review this patent when assessing their IP portfolios and R&D programs.

Archived snapshot

Mar 31, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Compounds and uses thereof

Grant US12590079B2 Kind: B2 Mar 31, 2026

Assignee

FOGHORN THERAPEUTICS INC.

Inventors

Sabine K. Ruppel, Zhaoxia Yang, Jason T. Lowe

Abstract

The present disclosure features compounds useful for the treatment of BAF complex-related disorders.

CPC Classifications

C07D 401/14 C07D 471/04 C07D 471/10 C07D 487/04 A61P 35/00

Filing Date

2020-07-31

Application No.

17631791

Claims

20

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Last updated

Classification

Agency
USPTO
Published
March 31st, 2026
Instrument
Notice
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US12590079B2

Who this affects

Applies to
Pharmaceutical companies Patients
Industry sector
3254 Pharmaceutical Manufacturing
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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