Changeflow GovPing Pharma & Drug Safety Evotec Heterocyclic Drug Patent, Apr 14
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Evotec Heterocyclic Drug Patent, Apr 14

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Evotec Heterocyclic Drug Patent, Apr 14

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Apr 15, 2026

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Modulators of the integrated stress response pathway

Grant US12600720B2 Kind: B2 Apr 14, 2026

Assignee

Evotec International GmbH

Inventors

Holly Victoria Atton, Mohamad Sabbah

Abstract

The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, R4, R4a, R4b, R4c, R4d, R4e, R5, R6 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating or preventing of one or more diseases or disorders associated with integrated stress response.

CPC Classifications

C07D 413/04

Filing Date

2021-10-21

Application No.

18033317

Claims

18

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