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EPO Patent Publication EP4626870A1 on Noncovalent KEAP1-NRF2 Inhibitors

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Published March 11th, 2026
Detected March 26th, 2026
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Summary

The European Patent Office has published patent application EP4626870A1 concerning noncovalent KEAP1-NRF2 small-molecule inhibitors. The publication lists the University of Copenhagen as the applicant and details inventors and IPC classifications related to organic chemistry and pharmaceutical applications.

What changed

The European Patent Office (EPO) has published patent application EP4626870A1, detailing novel small-molecule inhibitors targeting the KEAP1-NRF2 pathway. The application, filed by the University of Copenhagen, includes specific chemical classifications (IPC) related to organic chemistry and pharmaceutical uses, such as A61K 31/345 and A61P 35/00 (cancer treatment).

This publication represents a new patent filing and does not impose immediate compliance obligations on regulated entities. However, it is relevant for pharmaceutical companies and researchers in the drug discovery space, particularly those working on treatments for cancer, autoimmune diseases, and neurological disorders, as it may affect intellectual property landscapes and future research directions.

Source document (simplified)

← EPO Patent Bulletin

NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS

Publication EP4626870A1 Kind: A1 Mar 11, 2026

Applicants

University of Copenhagen

Inventors

LIN, Chunyu, ZANG, Jie, NARAYANAN, Dilip, BACH, Anders

IPC Classifications

C07D 249/18 20060101AFI20240607BHEP C07D 307/81 20060101ALI20240607BHEP C07D 317/60 20060101ALI20240607BHEP C07D 319/18 20060101ALI20240607BHEP A61K 31/345 20060101ALI20240607BHEP A61K 31/352 20060101ALI20240607BHEP A61K 31/4192 20060101ALI20240607BHEP A61K 31/36 20060101ALI20240607BHEP A61P 25/00 20060101ALI20240607BHEP A61P 35/00 20060101ALI20240607BHEP A61P 37/00 20060101ALI20240607BHEP C07D 405/06 20060101ALI20240607BHEP C07D 417/06 20060101ALI20240607BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

View original document →

Named provisions

NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS

Classification

Agency
EPO
Published
March 11th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
EP4626870A1

Who this affects

Applies to
Drug manufacturers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Discovery Patent Filing
Geographic scope
European Union EU

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Drug Discovery Intellectual Property

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