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Method and device for high field strength electrotransfection of microvesicles and cells

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Summary

The USPTO granted Patent US12594556B2 to The Charles Stark Draper Laboratory, Inc. covering a method and device for high field strength electrotransfection of microvesicles and cells using microfluidic arrangements under elevated pressure. The patent contains 18 claims and lists four inventors: Jonathan R. Coppeta, Timothy J. Biliouris, Daniel F. King, and Vishal Tandon.

What changed

The USPTO issued Patent US12594556B2 to The Charles Stark Draper Laboratory, Inc. for a device, system, and process involving electroporation of microvesicles, exosomes, or other target structures in a microfluidic arrangement operating at pressures exceeding atmospheric pressure. The technology supports single and multiple flow configurations with computer-controlled partial or complete automation. The patent contains 18 claims and was filed on November 21, 2023, under application number 18515386.

Patent grants are informational notices establishing intellectual property rights and do not impose compliance deadlines, required actions, or penalties. Technology companies, pharmaceutical manufacturers, and medical device developers working in electroporation, gene delivery, or exosome manipulation should review the claims to assess potential freedom-to-operate implications or licensing opportunities. No immediate regulatory action is required.

Archived snapshot

Apr 7, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Grants

Method and device for high field strength electrotransfection of microvescicles and cells

Grant US12594556B2 Kind: B2 Apr 07, 2026

Assignee

The Charles Stark Draper Laboratory, Inc.

Inventors

Jonathan R. Coppeta, Timothy J. Biliouris, Daniel F. King, Vishal Tandon

Abstract

A device, system and process involve conducting electroporation of microvesicles or exosomes or other target structures in a microfluidic arrangement at pressures that exceed atmospheric pressure. Single as well as multiple flow configurations can be employed. In some cases, the system and its operation are computer-controlled for partial or complete automation.

CPC Classifications

C12M 1/42 C12M 41/40 C12N 13/00 C12N 15/87 B01L 2300/0645 B01L 3/502715 B01L 2200/0647 B01L 3/50273 B01L 2300/047 B01L 2300/06 B01L 2300/0809 B01L 2300/14 B01L 2400/0421 B01L 2400/0424 B01L 2400/0496 B01L 3/5027 B01L 3/502753

Filing Date

2023-11-21

Application No.

18515386

Claims

18

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Named provisions

Abstract Claims CPC Classifications Filing Date Application No.

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Last updated

Classification

Agency
USPTO
Published
April 7th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12594556B2

Who this affects

Applies to
Technology companies Medical device makers Pharmaceutical companies
Industry sector
3341 Computer & Electronics Manufacturing 3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Biotech Research & Development Pharmaceutical Manufacturing Medical Device Innovation
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Biotechnology Pharmaceuticals

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