Dimeric Compounds as Inhibitors of Glycogen Synthase 1 (Gys1)
Summary
The European Patent Office has published patent application EP4587118A1 for dimeric compounds that inhibit Glycogen Synthase 1 (Gys1). The application lists Maze Therapeutics, Inc. as the applicant and details various inventors. This publication relates to potential new therapeutic agents.
What changed
European Patent Office (EPO) publication EP4587118A1 details a new patent application for dimeric compounds designed to inhibit Glycogen Synthase 1 (Gys1). The application, filed by Maze Therapeutics, Inc., outlines methods of use for these compounds, suggesting potential applications in therapeutic areas including metabolic disorders and cancer, as indicated by the IPC classifications.
This is a patent publication, not a regulatory rule or guidance with compliance obligations. Regulated entities in the pharmaceutical sector, such as drug manufacturers and pharmaceutical companies, should note this development as it pertains to potential new intellectual property in the field of drug discovery and development. No immediate compliance actions are required.
Source document (simplified)
DIMERIC COMPOUNDS AS INHIBITORS OF GLYCOGEN SYNTHASE 1 (GYS1) AND METHODS OF USE THEREOF
Publication EP4587118A1 Kind: A1 Mar 18, 2026
Applicants
Maze Therapeutics, Inc.
Inventors
MORGANS JR., David John, MELLEM, Kevin, LEE, Patrick Sang Tae, SINZ, Christopher Joseph, SCHAMMEL, Alexander Wayne, ZIEBENHAUS, Chris, WAHLERS, Jessica, TZITZILONIS, Christos, FASTMAN, Nathan
IPC Classifications
A61P 5/00 20060101AFI20240322BHEP A61P 25/00 20060101ALI20240322BHEP A61P 35/00 20060101ALI20240322BHEP C07D 213/61 20060101ALI20240322BHEP C07D 401/14 20060101ALI20240322BHEP A61K 31/4439 20060101ALI20240322BHEP A61K 31/444 20060101ALI20240322BHEP A61K 47/50 20170101ALI20240322BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
Named provisions
Related changes
Source
Classification
Who this affects
Taxonomy
Browse Categories
Get Pharma & Drug Safety alerts
Weekly digest. AI-summarized, no noise.
Free. Unsubscribe anytime.
Get alerts for this source
We'll email you when ChangeBridge: EPO Bulletin - Pharma (A61K) publishes new changes.