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Washington University Patent Grant - Conjugate Systems

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Published March 24th, 2026
Detected March 24th, 2026
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Summary

The USPTO has granted Washington University a patent (US12584145B2) for conjugate systems and methods of use thereof. The patent describes adenovirus conjugates with peptide tags for binding partners, relevant to biotechnology and pharmaceutical applications.

What changed

The United States Patent and Trademark Office (USPTO) has issued patent grant US12584145B2 to Washington University for "Conjugate systems and methods of use thereof." The patent details a conjugate system involving an adenovirus with a peptide tag on its exterior surface, designed to bind to a specific partner. This grant is associated with CPC classification C12N 15/86 and was filed on April 15, 2023, with 25 claims.

This patent grant is primarily an intellectual property notification and does not impose new regulatory obligations on regulated entities. However, companies in the biotechnology and pharmaceutical sectors, particularly those involved in drug development or gene therapy, may find this patent relevant to their research and development activities. Compliance officers should note this patent as part of their landscape monitoring for intellectual property in relevant therapeutic areas.

Source document (simplified)

← USPTO Patent Grants

Conjugate systems and methods of use thereof

Grant US12584145B2 Kind: B2 Mar 24, 2026

Assignee

Washington University

Inventors

David Curiel, Zhi Hong Lu

Abstract

Among the various aspects of the present disclosure is the provision of conjugate systems and methods of use thereof. In an aspect, the conjugate system includes an adenovirus comprising an exterior surface, and at least one polypeptide comprising a first domain and a second domain, and wherein the exterior surface comprises a peptide tag capable of binding to a binding partner.

CPC Classifications

C12N 15/86

Filing Date

2023-04-15

Application No.

18301228

Claims

25

View original document →

Named provisions

Conjugate systems and methods of use thereof

Source

Analysis generated by AI. Source diff and links are from the original.

Classification

Agency
USPTO
Published
March 24th, 2026
Instrument
Notice
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
US12584145B2

Who this affects

Applies to
Drug manufacturers Medical device makers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing 3254.1 Biotechnology
Activity scope
Drug Development Biotechnology Research
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Research & Development
Topics
Biotechnology Intellectual Property

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