Acetohydroxy acid synthase variant and microorganism including the same

USPTO granted patent US12590128B2 to CJ CheilJedang Corporation for an acetohydroxy acid synthase variant, polynucleotides encoding the variant, microorganisms including the variant, and a method of producing L-isoleucine using the microorganism. The patent was granted March 31, 2026, with 20 claims. Application No. 17778810.

Third parties should be aware that CJ CheilJedang now holds exclusive rights to this technology. Competitors in the L-isoleucine production space may need to design around this patent or seek licenses. The patent filing date was June 10, 2020, meaning the patent protection extends 20 years from that date.