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Cells, Organs with Modified Genes for Xenograft Tolerance

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Summary

Cells, Organs with Modified Genes for Xenograft Tolerance

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Apr 12, 2026

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CELLS, TISSUES, ORGANS, AND ANIMALS HAVING ONE OR MORE MODIFIED GENES FOR ENHANCED XENOGRAFT SURVIVAL AND TOLERANCE

Application US20260098278A1 Kind: A1 Apr 09, 2026

Inventors

Jacob LAYER, Wenning QIN, Yinan KAN, Juliet CRABTREE, Michele YOUD, David HEJA, David ANGELES ALBORES, Ranjith ANAND, Paola PERRAT, Russell ERNST, Violette PARAGAS

Abstract

The present disclosure relates to cells, tissues, organs, and/or animals having one or more modified genes for enhanced xenograft survival and/or tolerance. In addition, the present disclosure relates to methods of making and using the cells, tissues, organs, and/or animals having one or more of the modified genes.

CPC Classifications

C12N 15/85 A01K 67/0276 C07K 14/4747 C07K 14/70503 C07K 14/70596 C07K 14/7455 C12N 9/0083 C12Y 114/99003 A01K 2207/12 A01K 2227/108 A01K 2267/025 C12N 2830/20 C12N 2830/50

Filing Date

2025-12-09

Application No.

19414047

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