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CD19/CD22 CAR T Cell Treatment for High-Risk Pediatric Acute Lymphoblastic Leukemia

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Summary

The USPTO published patent application US20260097122A1 for CD19/CD22 chimeric antigen receptor (CAR) T-cell products and methods for treating high-risk or relapsed CD19+ or CD22+ haematological malignancies, specifically pediatric acute lymphoblastic leukemia. The application was filed on May 10, 2023, under application number 18862269. Inventors include Martin Pulé, Persis Amrolia, and Sara Ghorashian.

What changed

The USPTO published a patent application covering CD19/CD22 CAR T-cell products and associated treatment methods for CD19+ or CD22+ haematological malignancies, with particular focus on high-risk or relapsed pediatric acute lymphoblastic leukemia. The application includes CPC classifications related to therapeutic compositions and methods.

For biotechnology and pharmaceutical companies developing CAR T-cell or related cell therapy products, this published application represents prior art that may affect freedom to operate assessments. Competitors should evaluate whether their development programs may overlap with the claimed subject matter to identify potential licensing needs or design-around opportunities.

What to do next

  1. Monitor patent prosecution status
  2. Assess freedom to operate for CAR T-cell development programs

Archived snapshot

Apr 13, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

CD19/C22 CAR T-CELL TREATMENT OF HIGH RISK OR RELAPSED PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA

Application US20260097122A1 Kind: A1 Apr 09, 2026

Inventors

Martin Pulé, Persis Amrolia, Sara Ghorashian

Abstract

The present disclosure relates to CD19/22 CAR T-cell products and methods for treating high risk or relapsed CD19+ or CD22+ haematological malignancies.

CPC Classifications

A61K 40/4211 A61K 40/11 A61K 40/31 A61K 40/4212 A61P 35/02 A61K 2239/13 A61K 2239/28 A61K 2239/48

Filing Date

2023-05-10

Application No.

18862269

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Last updated

Classification

Agency
USPTO
Published
April 9th, 2026
Instrument
Rule
Legal weight
Binding
Stage
Final
Change scope
Minor
Document ID
US20260097122A1
Docket
18862269

Who this affects

Applies to
Pharmaceutical companies Healthcare providers Biotechnology companies
Industry sector
3254.1 Biotechnology
Activity scope
Patent filing Cell therapy development Biopharmaceutical research
Geographic scope
United States US

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Healthcare Pharmaceuticals

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