Pyrimidine Derivative for Inflammation Treatment
Summary
USPTO published patent application US20260092044A1 by ASKA Pharmaceutical Co., Ltd. for a pyrimidine derivative with mPGES-1 inhibitory activity for treating inflammation, pain, and rheumatism. The application was filed December 8, 2025, and names Makoto Okada, Youichi Nakano, Takashi Nose, Satoshi Maeda, and Tomoaki Watanabe as inventors.
What changed
The USPTO published patent application US20260092044A1 disclosing a pyrimidine derivative compound of formula (I) as an mPGES-1 inhibitor for pharmaceutical use. The compound (R represents methyl group or fluorine atom) is intended for prophylactic and/or therapeutic treatment of inflammation, pain, or rheumatism. The application classifies under CPC C07D 401/04 and names ASKA Pharmaceutical Co., Ltd. as assignee.
This is a patent application publication, not a regulatory action imposing obligations. Pharmaceutical companies and researchers developing mPGES-1 inhibitors should review the application to assess potential freedom-to-operate implications for their own compounds. No compliance deadlines or regulatory actions apply to this document.
Archived snapshot
Apr 2, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
PYRIMIDINE DERIVATIVE
Application US20260092044A1 Kind: A1 Apr 02, 2026
Assignee
ASKA PHARMACEUTICAL CO., LTD.
Inventors
Makoto OKADA, Youichi NAKANO, Takashi NOSE, Satoshi MAEDA, Tomoaki WATANABE
Abstract
A compound of the formula (I) or a salt thereof (R represents methyl group or fluorine atom) having an mPGES-1 inhibitory activity and useful as an active ingredient of a medicament for prophylactic and/or therapeutic treatment of such diseases as inflammation, pain, or rheumatism.
CPC Classifications
C07D 401/04
Filing Date
2025-12-08
Application No.
19412285
Named provisions
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