Amide compounds activate potassium channels for CNS/PNS disorders
ChangeBridge: EPO Bulletin - Organic Chemistry (C07D)
Summary
The European Patent Office has published patent application EP4630406A1 concerning amide compounds that activate potassium channels, useful for treating CNS and PNS disorders. The patent application was filed by Angelini Pharma S.P.A. and lists several inventors.
What changed
This document is a publication of a European patent application (EP4630406A1) by Angelini Pharma S.P.A. The patent describes novel amide compounds designed to activate KV7.2/KV7.3 potassium channels, which are indicated for the treatment of Central Nervous System (CNS) and Peripheral Nervous System (PNS) disorders. The publication date is March 11, 2026.
As this is a patent publication, it does not impose direct compliance obligations on regulated entities. However, it signifies potential future developments in pharmaceutical treatments for neurological conditions. Companies involved in drug development, particularly in the CNS/PNS therapeutic areas, should be aware of this patent filing as it may impact their research and development strategies or intellectual property landscape.
Source document (simplified)
AMIDE COMPOUNDS AS ACTIVATORS OF THE POTASSIUM CHANNELS KV7.2/KV7.3 USEFUL IN THE TREATMENT OF CNS AND PNS DISORDERS
Publication EP4630406A1 Kind: A1 Mar 11, 2026
Applicants
ANGELINI PHARMA S.P.A.
Inventors
GAROFALO, Barbara, OMBRATO, Rosella, PRATI, Federica, PALLIN, Thomas David, KNIGHT, Jamie David, SAVY, Pascal
IPC Classifications
C07D 213/64 20060101AFI20240614BHEP A61P 25/00 20060101ALI20240614BHEP A61K 31/44 20060101ALI20240614BHEP C07D 213/65 20060101ALI20240614BHEP C07D 213/68 20060101ALI20240614BHEP C07D 213/74 20060101ALI20240614BHEP C07D 239/34 20060101ALI20240614BHEP C07D 401/04 20060101ALI20240614BHEP C07D 401/12 20060101ALI20240614BHEP C07D 405/12 20060101ALI20240614BHEP C07D 409/12 20060101ALI20240614BHEP C07D 413/12 20060101ALI20240614BHEP C07D 498/08 20060101ALI20240614BHEP A61K 31/4439 20060101ALI20240614BHEP A61K 31/444 20060101ALI20240614BHEP A61K 31/4436 20060101ALI20240614BHEP A61K 31/443 20060101ALI20240614BHEP A61K 31/4433 20060101ALI20240614BHEP
Designated States
AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, ME, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR
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