High-resolution ultrasonography of gingival biomarkers for periodontal diagnosis
Summary
The USPTO granted patent US12588888B2 to The Regents of the University of California for a method of periodontal disease diagnosis using B-mode ultrasound imaging. The patent covers identifying specific gingival biomarkers (GM, ABC, CEJ, PDL, GE) to evaluate periodontal disease metrics and guide therapeutic treatment. The patent names Jesse Vincent Jokerst, Colman Arthur Moore, and Casey Chen as inventors.
What changed
The USPTO granted Patent No. US12588888B2 for a method of measuring periodontal disease via high-resolution ultrasonography. The patent covers obtaining B-mode ultrasound images of dentition and periodontium, identifying five gingival biomarkers (gingival margin, alveolar bone crest, cementoenamel junction, periodontal ligament, and gingival edge), and using these biomarkers to evaluate periodontal disease and adjust therapeutic treatment. The patent includes 8 claims and is assigned to The Regents of the University of California.
Medical device manufacturers developing ultrasound imaging equipment for dental applications should review this patent to assess freedom-to-operate considerations. Healthcare providers utilizing periodontal ultrasound diagnostics should verify licensing or royalty obligations. No immediate compliance deadline applies, as patent grants do not create regulatory obligations but rather establish intellectual property rights.
Archived snapshot
Mar 31, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
High-resolution ultrasonography of gingival biomarkers for periodontal diagnosis in healthy and diseased subjects
Grant US12588888B2 Kind: B2 Mar 31, 2026
Assignee
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors
Jesse Vincent Jokerst, Colman Arthur Moore, Casey Chen
Abstract
A method for measuring periodontal disease and treating diseases associated therewith includes: obtaining B-mode ultrasound images of a dentition and periodontium of a patient; identifying gingival margin (GM), alveolar bone crest (ABC), cementoenamel junction (CEJ), periodontal ligament (PDL), and gingival edge (GE) biomarkers on the B-mode ultrasound images, the GE biomarker being a part of periodontal soft tissue most distal from a tooth surface; evaluating a metric associated with periodontal disease using one or more of the GM, ABC, CEJ, PDL and GE biomarkers and based at least in part on the evaluating, performing an act that implements and/or adjusts a therapeutic treatment of a periodontal disease.
CPC Classifications
A61B 8/0858 A61B 8/0833 A61B 8/0875 A61C 19/04
Filing Date
2022-11-07
Application No.
18706898
Claims
8
Named provisions
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