CT Imaging Method for Vasa Vasorum Density Measurement in Vascular Wall
Summary
USPTO granted Patent US12599350B2 to inventor Morteza Naghavi on April 14, 2026. The patent covers a computed tomography method for imaging vasa vasorum density in blood vessels including coronary and carotid arteries and the aorta. The method involves administering a contrast agent, performing contrast-enhanced CT scans, measuring Hounsfield distribution, and analyzing data to determine vasa vasorum density metrics for assessing cardiovascular risk and recommending diagnostic or therapeutic next steps.
What changed
USPTO granted Patent US12599350B2 to Morteza Naghavi, covering a CT-based imaging method for measuring vasa vasorum density in vascular walls. The method involves administering a contrast agent, performing contrast-enhanced CT scans, analyzing Hounsfield distribution and heterogeneity related to vasa vasorum density, and recommending diagnostic or therapeutic interventions based on the measurements. The patent contains 17 claims spanning imaging methods, data analysis, and clinical recommendations for cardiovascular risk assessment.
Medical device manufacturers developing CT imaging software or contrast-enhanced imaging technologies should review this patent to assess potential licensing needs or design-around considerations. Healthcare providers performing cardiovascular imaging may need to monitor patent portfolios for similar diagnostic technologies. The patent's scope covers imaging systems and methods for assessing inflammation and angiogenesis in vascular walls using vasa vasorum density as a biomarker.
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Apr 14, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Computed tomography based imaging of vasa vasorum density for detection and monitoring of inflammation and angiogenesis in vascular wall
Grant US12599350B2 Kind: B2 Apr 14, 2026
Inventors
Morteza Naghavi
Abstract
According to an aspect of the present invention, there is provided a method for imaging vasa vasorum density of a vessel in the body such as coronary and carotid arteries and the aorta and thereby assessing the risk of adverse health outcomes for a patient, comprising administering a contrast agent to the patient; performing a contrast-enhanced CT scan to measure Hounsfield distribution and heterogeneity related to vasa vasorum density in and around the vessel wall of a patient; analyzing the data to determine a metric related to the density of the vasa vasorum; and recommending a diagnostic and/or therapeutic next step to the patient to prevent adverse health outcomes based at least in part on the metric related to the vasa vasorum density.
CPC Classifications
A61B 6/504 A61B 6/481 A61B 6/4417 A61B 8/12 A61B 6/503 A61B 6/5217 A61B 8/0883 A61B 8/0891 A61B 8/4416 A61B 6/032 G06T 7/0012 G06T 2207/10081 G06T 2207/30101
Filing Date
2023-09-18
Application No.
18469384
Claims
17
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