Cryogenic Catheter Probe for Gastrointestinal Tract Ablation
Summary
The USPTO granted patent US12599424B2 to Agil Therapeutics, Inc. on April 14, 2026. The patent covers a cryogenic catheter probe, system, and method for selective ablation of mucosal and submucosal tissue in the gastrointestinal tract. The invention includes a chamber with a central rail, cryogenic fluid delivery channels, and a sprayer configured to release cryogenic spray in treatment zones along the chamber. The patent contains 17 claims.
What changed
USPTO granted patent US12599424B2 to Agil Therapeutics covering a cryogenic catheter probe for selective ablation of mucosa and submucosa in the gastrointestinal tract. The patented system includes a chamber with a central rail, cryogenic fluid delivery channels with sprayers, and components configured for longitudinal movement along the rail to deliver cryogenic spray to targeted treatment zones.
For competitors in the medical device space developing ablation technologies for GI applications, this patent establishes intellectual property rights that may require licensing or design-around strategies. Medical device manufacturers working on cryoablation or endoscopic mucosal resection technologies should conduct freedom-to-operate analyses to assess potential infringement risks.
What to do next
- Monitor for potential licensing opportunities
- Review patent claims for freedom-to-operate analysis
Archived snapshot
Apr 14, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Cryogenic catheter probe, system, and method for selective ablation of mucosa and submucosa of the gastrointestinal tract
Grant US12599424B2 Kind: B2 Apr 14, 2026
Assignee
AGIL THERAPEUTICS, INC.
Inventors
Peter Garcia-Meza, Timothy D. Holland
Abstract
Disclosed is a cryogenic catheter probe, cryogenic ablation system, and use thereof for performing cryogenic ablation of mucosal tissue and/or of both mucosal tissue and submucosal tissue in the gastrointestinal tract of a subject. The cryogenic catheter probe includes a chamber and a channel assembly housed within the chamber. The channel assembly includes a central rail, at least one cryogenic fluid delivery channel, a delivery channel guide, and a sprayer guide. The at least one cryogenic fluid delivery channel has a fluid delivery channel portion and a sprayer connected to the fluid delivery channel portion, and is mounted on the central rail for longitudinal movement along the central rail. The sprayer is configured to release cryogenic spray in at least one treatment zone along the hollow body portion of the chamber.
CPC Classifications
A61B 18/02 A61B 18/0218 A61B 2018/00184 A61B 2018/00196 A61B 2018/0022 A61B 2018/00482 A61B 2018/00488 A61B 2018/00494 A61B 2018/008 A61B 2018/00577 A61B 2018/00642 A61B 2018/00708 A61B 2018/00744 A61B 2018/00773 A61B 2018/0212
Filing Date
2022-06-07
Application No.
18568225
Claims
17
Named provisions
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Source
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