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Vitamin D3 Supplementation in HIV Patients: Effects on IL-6 and CD4 Counts

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Summary

This ClinicalTrials.gov record (NCT07553052) registers an interventional study evaluating Vitamin D3 supplementation over 3 months in patients with HIV receiving antiretroviral therapy. The trial will measure Interleukin-6 levels and CD4 counts as primary outcomes to assess the effect of Vitamin D3 on inflammatory markers and immune status. The study is registered with NIH and open to participants meeting HIV and antiretroviral therapy criteria.

“Participants will receive Vitamin D3 supplementation for 3 months.”

NIH , verbatim from source
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About this source

ClinicalTrials.gov is the NIH-run registry of every clinical trial conducted in the United States, plus most international trials sponsored by US-based companies or institutions. By federal law, sponsors must register Phase 2 through Phase 4 studies before enrolling patients and post results within a year of completion. This feed tracks every new trial registration and study update, around 700 a month: drug interventions, device studies, behavioral protocols, observational research. Watch this if you scout drug candidates moving into mid or late-stage development, monitor competitor pipelines, or follow rare disease research where new trials signal patient hope. GovPing parses sponsor, phase, intervention, and target indication on each entry.

What changed

This is a clinical trial registration entry for a prospective interventional study on ClinicalTrials.gov, not a regulatory rule or guidance document. The study enrolls HIV-positive participants on antiretroviral therapy and administers Vitamin D3 supplementation for 3 months, with Interleukin-6 levels and CD4 counts as measured outcomes.

Affected parties — clinical investigators, trial sponsors, and healthcare providers conducting or referencing HIV adjuvant therapy research — should note this trial is registered and active. The study may inform future clinical practice regarding vitamin D3 adjunctive therapy in HIV management if statistically significant improvements in immune markers are demonstrated.

Archived snapshot

Apr 28, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Vitamin D3 Supplementation in Patients With HIV: Effects on Interleukin-6 Levels and CD4 Counts

N/A NCT07553052 Kind: NA Apr 27, 2026

Abstract

This study aims to evaluate the effect of Vitamin D3 supplementation on inflammatory markers and immune status in patients with HIV who are receiving antiretroviral therapy. Participants will receive Vitamin D3 supplementation for 3 months. Outcomes including Interleukin-6 levels and CD4 counts will be measured to assess the potential benefits of this intervention.

Conditions: Human Immunodeficiency Virus (HIV)

Interventions: Vitamin D3, Antiretroviral (ARV) medications

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Last updated

Classification

Agency
NIH
Published
April 27th, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07553052

Who this affects

Applies to
Clinical investigators Healthcare providers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Clinical trial registration Drug research
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Regulatory Affairs
Topics
Healthcare Public Health

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