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Viral Respiratory Infection Treatment Methods, Gradalis, Inc., EP4158025A1

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Summary

The European Patent Office published application EP4158025A1 for Gradalis, Inc. on April 15, 2026. The patent covers methods for treating viral respiratory infections using nucleic acid sequences classified under C12N 15/113, with pharmaceutical compositions containing A61K 38/19 and A61K 31/713. The application designates 31 European states including AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, and TR. Inventors include David Shanahan, John Nemunaitis, and Ernest Bognar.

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GovPing monitors EPO Patent Bulletin - Biotech (C12N) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 61 changes logged to date.

What changed

The EPO published patent application EP4158025A1 for Gradalis, Inc., covering methods of treating viral respiratory infections. The application claims compositions including C12N 15/113 nucleic acid sequences, A61K 38/19 protein compositions, and A61K 31/713 antisense or short interfering RNA formulations targeting A61P 31/14 viral pathogens and A61P 11/00 respiratory conditions. The patent provides Gradalis exclusive rights across 31 designated European contracting states for the claimed therapeutic methods.

Pharmaceutical and biotechnology companies developing RNA-based or nucleic acid-based antiviral respiratory therapies should review the claims of EP4158025A1 to assess potential freedom-to-operate considerations in European markets. Generic drug manufacturers and biosimilar developers may need to design around these claims when developing competing respiratory infection treatments for the designated states.

Archived snapshot

Apr 25, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← EPO Patent Bulletin

METHODS FOR THE TREATMENT OF VIRAL RESPIRATORY INFECTIONS

Publication EP4158025A1 Kind: A1 Apr 15, 2026

Applicants

Gradalis, Inc.

Inventors

SHANAHAN, David, NEMUNAITIS, John, BOGNAR, Ernest

IPC Classifications

C12N 15/113 20100101AFI20211203BHEP A61K 38/19 20060101ALI20211203BHEP A61K 31/713 20060101ALI20211203BHEP A61P 31/14 20060101ALI20211203BHEP A61P 11/00 20060101ALI20211203BHEP

Designated States

AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR

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Last updated

Classification

Agency
EPO
Published
April 15th, 2026
Instrument
Notice
Branch
International
Legal weight
Binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies
Industry sector
3254.1 Biotechnology
Activity scope
Patent grant Therapeutic method claims Nucleic acid compositions
Geographic scope
European Union EU

Taxonomy

Primary area
Intellectual Property
Operational domain
Legal
Topics
Pharmaceuticals Public Health

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