Changeflow GovPing Healthcare & Life Sciences USPTO Patent Applications - Peptides (C07K)
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USPTO Patent Applications - Peptides (C07K)

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USPTO classification C07K covers peptides: short amino-acid chains that form the backbone of antibodies, hormones, vaccines, and increasingly a wider class of therapeutic modalities. Every newly published application in C07K lands in this feed, around 175 a month. Applications publish 18 months after filing, so this feed reveals what antibody engineering groups, vaccine developers, and plant biotech researchers were working on in the prior year and a half. Watch this if you compete in biologics, file freedom-to-operate analyses on antibody drug candidates, scout acquisition targets in vaccine platforms, or track protein-based agricultural biotech filings.

Thursday, March 26, 2026

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USPTO Patent Application: Phage T4 Nanoparticle Vaccine Platform

The USPTO has published a patent application (US20260083835A1) detailing a modular bacteriophage T4 nanoparticle vaccine platform. This platform is designed for the rapid development of dual COVID-19 and flu mucosal vaccines, administered intranasally without an adjuvant.

Routine Notice Healthcare
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USPTO Patent Application: Modified Coronavirus Spike Antigen Protein

The USPTO has published a patent application (US20260083836A1) for a modified coronavirus spike antigen protein. The application describes a protein designed to suppress cell membrane fusion ability and improve safety by modifying cleavage sites, aiming to enhance vaccine efficacy and antibody production.

Routine Notice Pharmaceuticals
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USPTO Patent Application: Treating NSCLC with Dostarlimab or Biosimilar

The USPTO has published a patent application detailing a method for treating non-small cell lung cancer (NSCLC) using dostarlimab or a biosimilar. The application outlines a treatment approach for patients previously treated with an immune checkpoint inhibitor.

Routine Notice Pharmaceuticals
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USPTO Patent Application: NEO-201 Antibody for Suppressing Myeloid Derived Suppressor Cells

The USPTO has published a patent application (US20260083840A1) detailing methods for ablating myeloid derived suppressor cells using the NEO-201 antibody. The application describes the antibody's specific binding to certain O-glycans and its potential use in treating cancers and infectious diseases by suppressing gMDSCs.

Routine Notice Healthcare
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Bispecific Molecule Stabilizing Composition Patent Application

The USPTO has published a patent application (US20260083841A1) for a pharmaceutical composition designed to stabilize bispecific antigen-binding molecules at increased concentrations. The composition includes buffer agents, saccharides, and specific stabilizing agents like EDTA or citric acid.

Routine Notice Pharmaceuticals
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USPTO Patent Application: IL-17 Antibody Compositions

The USPTO has published a patent application (US20260083842A1) detailing pharmaceutical products and stable liquid compositions of IL-17 antibodies, such as secukinumab. The application covers methods of making these compositions and their use in treating IL-17-mediated disorders, including autoimmune conditions like psoriasis and rheumatoid arthritis.

Routine Notice Pharmaceuticals

Monday, March 23, 2026

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USPTO Patent Application for Multivalent CLTX-CAR γδ T-cells

The USPTO has published a patent application (US20260078529A1) for multivalent CLTX-CAR γδ T-cells, which are designed for treating cancer or tumors. The application details specific T-cell compositions, pharmaceutical formulations, and methods of co-administering these cells with chemotherapeutic agents.

Routine Notice Healthcare
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USPTO Patent Application: Orthogonal Mutations for Heterodimerization

The USPTO has published a patent application (US20260078202A1) detailing orthogonal mutations for heterodimerizing domains, particularly in antibody CH3 domains. This application, filed on April 25, 2025, by Jonathan Harry Davis and Nicholas M. Marshall, describes heterodimeric polypeptides and antibody constructs.

Routine Notice Pharmaceuticals
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USPTO Patent Application for Tau Phospho Binding Antibodies

The USPTO has published a patent application (US20260079168A1) for Tau phospho binding antibodies and antigen binding fragments thereof. The application, filed on September 15, 2025, relates to methods for detecting Tau phospho (Thr217) and potential diagnostic or therapeutic uses for diseases associated with it.

Routine Notice Healthcare
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USPTO Patent Application: Pathogen Surrogates for Fresh Produce Sanitation

The USPTO has published a patent application (US20260079142A1) detailing pathogen surrogates with DNA tags for verifying sanitation systems in fresh produce processing. The application describes a method using these surrogates to mimic pathogen behavior during sanitation and subsequent DNA detection.

Routine Notice Food Safety
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USPTO Patent Application: Ultrasensitive Immunoassay Method and Reagents

The USPTO has published a patent application detailing a new method and reagents for ultrasensitive detection of target molecules using reconstituted functional proteins. The invention aims to improve specificity and signal-to-noise ratios in various assay formats, including those for detecting viruses, bacteria, and proteins.

Routine Notice Healthcare

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