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USPTO Patent Application for Acute Migraine Treatment with Ubrogepant

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Summary

The USPTO has published a new patent application (US20260083710A1) detailing methods for the acute treatment of migraine using the drug ubrogepant. The application includes specific claims related to treatment in patients with hepatic or renal impairment and those concurrently taking certain CYP3A4 modulators or BCRP/P-gp inhibitors.

Published by USPTO on changeflow.com . Detected, standardized, and enriched by GovPing. Review our methodology and editorial standards .

What changed

The United States Patent and Trademark Office (USPTO) has published a patent application, US20260083710A1, concerning methods for the acute treatment of migraine. The application specifically covers the administration of ubrogepant, with particular emphasis on its use in patients experiencing hepatic or renal impairment, or those concurrently taking specific CYP3A4 modulators or BCRP and/or P-gp only inhibitors.

This publication represents a new patent application filing and does not impose immediate regulatory obligations on pharmaceutical companies. However, it signifies potential future intellectual property protection for ubrogepant-based migraine treatments, which may impact market exclusivity and competitive strategies for companies operating in the migraine therapeutic space. Companies developing or marketing similar treatments should monitor the progress of this patent application and consider its implications for their own product pipelines and intellectual property portfolios.

Archived snapshot

Mar 27, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← USPTO Patent Applications

TREATMENT OF MIGRAINE

Application US20260083710A1 Kind: A1 Mar 26, 2026

Inventors

Joel M. Trugman, Ramesh Boinpally, Abhijeet Jakate, Michelle Finnegan, Mary Ann Johnson, Leonardo R. Allain, W. Mark Eickhoff, Craig B. Ikeda, Chad D. Brown, Francis J. Flanagan, JR., Rebecca Nofsinger, Melanie J. Marota, Lisa Lupton, Paresh B. Patel, Hanmi Xi, Wei Xu

Abstract

The present disclosure provides methods for the acute treatment of migraine with or without aura, comprising the administration of ubrogepant. In particular, the present disclosure provides methods for the acute treatment of migraine in patients having hepatic impairment; in patients with renal impairment; and in patients concurrently taking CYP3A4 modulators or BCRP and/or P-gp only inhibitors.

CPC Classifications

A61K 31/4375 A61K 31/4545 A61P 25/06

Filing Date

2025-10-07

Application No.

19351985

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Named provisions

TREATMENT OF MIGRAINE

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Last updated

Classification

Agency
USPTO
Instrument
Notice
Legal weight
Non-binding
Stage
Draft
Change scope
Minor
Document ID
US20260083710A1

Who this affects

Applies to
Drug manufacturers
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Drug Development Pharmaceutical Manufacturing
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Legal
Compliance frameworks
FDA 21 CFR Part 11 GxP
Topics
Drug Development Intellectual Property

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