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TLK1B Inhibitor, Antiandrogen Prostate Cancer Treatment Patent

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USPTO classification A61P covers the therapeutic use of compounds: indications like cancer, inflammation, cardiovascular disease, CNS disorders, and rare diseases. Every patent grant in A61P lands in this feed, around 190 a month, with the patent number, title, applicant, inventor names, and abstract. A61P grants are frequently co-classified with composition-of-matter patents, so this feed is especially useful for mapping which chemical entities have secured both composition and method-of-use protection. Watch this if you run drug discovery, advise on biotech patent portfolios, scout in-licensing opportunities, or track antibody-drug conjugate and small-molecule oncology patent activity.

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Apr 28, 2026

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← USPTO Patent Grants

Targeting the TLK1/NEK1 axis in prostate cancer

Grant US12611412B2 Kind: B2 Apr 28, 2026

Assignee

Board of Supervisors of Louisana State University and Agricultural and Mechanical College

Inventors

Arrigo DeBenedetti, Siddhant Bhoir, Vibha Singh, Javeena Hussain, Rupesh Chikhale, Richard Bryce, Sivapriya Kirubakaran

Abstract

A method of treating prostate cancer in a patient comprising administering to the patient a pharmaceutical composition including a first therapeutic including a TLK1B inhibitor, or a pharmaceutically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analog thereof, and a second therapeutic including an antiandrogen or a pharmaceutically acceptable salt, solvate, ester, amide, clathrate, stereoisomer, enantiomer, prodrug or analog thereof.

CPC Classifications

A61K 31/5415 A61K 31/167 A61P 35/00

Filing Date

2023-11-15

Application No.

18509586

Claims

20

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