Substituted Indazoles IRAK4 Inhibitor Patent Application
Summary
The USPTO published patent application US20260092069A1 by inventors Terstiege, Schiesser, Xue, Chang, and Berggren for substituted indazoles as IRAK4 inhibitors with potential therapeutic utility. The application (No. 19343252) was filed September 29, 2025 and published April 2, 2026. IRAK4 inhibitors target inflammatory and autoimmune pathways.
What changed
The USPTO published a patent application covering chemical compounds of Formula (I) that inhibit IRAK4 (Interleukin-1 Receptor-Associated Kinase 4), along with their pharmaceutical salts. IRAK4 plays a role in innate immune signaling and inflammatory responses, making these compounds potential candidates for treating inflammatory, autoimmune, and allergic conditions. The application is classified under CPC codes C07D 487/04 with therapeutic indications A61P 11/06 (respiratory) and A61P 37/06 (immune disorders).
Pharmaceutical companies developing IRAK4 inhibitors or related anti-inflammatory therapeutics should review their pipelines for potential conflicts with the claimed compounds. Patent counsel may conduct freedom-to-operate analyses. This publication does not impose compliance deadlines or regulatory obligations—it is an informational record of a patent filing.
Archived snapshot
Apr 2, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
SUBSTITUTED INDAZOLES AS IRAK4 INHIBITORS
Application US20260092069A1 Kind: A1 Apr 02, 2026
Inventors
Ina TERSTIEGE, Stefan SCHIESSER, Yafeng XUE, Hui-Fang CHANG, Anna Ingrid Kristina BERGGREN
Abstract
The present application relates to chemical compounds of Formula (I), and pharmaceutically acceptable salts thereof, that inhibit IRAK4 and consequently have potential utility in medicine.
CPC Classifications
C07D 487/04 A61P 11/06 A61P 37/06
Filing Date
2025-09-29
Application No.
19343252
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