Serratus Block vs Intrathecal Morphine for Thoracoscopic Surgery, Opioid Consumption 24h
ClinicalTrials.gov Studies
Summary
A new clinical trial registration (NCT07540104) has been published on ClinicalTrials.gov for a prospective, randomized, controlled, single-center study based in the US. The trial will enroll adult patients undergoing elective video-assisted thoracoscopic surgery and randomly assign them to receive either serratus posterior superior intercostal plane block or intrathecal morphine prior to general anesthesia. The primary endpoint is cumulative opioid consumption at 24 postoperative hours measured in intravenous morphine milligram equivalents. Secondary endpoints include pain scores, time to first analgesic request, quality of recovery, and postoperative complications.
What changed
A new clinical trial has been registered on ClinicalTrials.gov (NCT07540104) without creating any new compliance obligations. The study is a prospective, randomized, controlled trial comparing serratus posterior superior intercostal plane block to intrathecal morphine for postoperative analgesia in thoracoscopic surgery patients. Trial sponsors and clinical investigators conducting similar analgesic research may wish to note this comparative effectiveness study as it may inform future trial design or evidence synthesis in regional anesthesia techniques.
Affected parties including clinical investigators, healthcare institutions conducting analgesic trials, and pharmaceutical companies involved in opioid or regional anesthesia products should note this registry entry for awareness purposes only. No regulatory obligations, reporting requirements, or compliance deadlines are created by this registration.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Serratus Posterior Superior Intercostal Plane Block Versus Intrathecal Morphine in VATs
N/A NCT07540104 Kind: NA Apr 20, 2026
Abstract
This study aims to compare the analgesic effects of the serratus posterior superior intercostal plane block and intrathecal morphine in patients undergoing video-assisted thoracoscopic surgery.
This is a prospective, randomized, controlled, single-center clinical trial including adult patients undergoing elective thoracoscopic surgery. Participants will be randomly assigned to receive either a serratus posterior superior intercostal plane block or intrathecal morphine before general anesthesia.
The primary outcome is cumulative opioid consumption during the first 24 postoperative hours, expressed as intravenous morphine milligram equivalents. Secondary outcomes include pain scores, time to first analgesic request, quality of recovery, and postoperative complications.
The study aims to determine whether these two techniques differ in their effectiveness for postoperative pain management.
Conditions: Thoracic Anesthesia, Postoperative Pain, Video Assisted Thoracic Surgery (VATS)
Interventions: Intrathecal Morphine, Serratus Posterior Superior Intercostal Plane Block
Related changes
Get daily alerts for ClinicalTrials.gov Studies
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from NIH.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when ClinicalTrials.gov Studies publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.