Quinoline cGAS Antagonist Solid Forms and Salts
Summary
The USPTO published patent application US20260092048A1 for solid forms and salts of a quinoline cGAS antagonist compound, filed by inventors Jian Qiu, Qi Wei, Heping Shi, Lijun Sun, and Zhijian Chen (Application No. 19316546, filed September 2, 2025). The application discloses the compound's cGAS antagonist properties, methods of preparation, pharmaceutical compositions, and use in medical therapy.
What changed
The patent application discloses novel solid forms and salts of a quinoline compound functioning as a cGAS (cyclic GMP-AMP synthase) antagonist, classified under CPC C07D 401/14. The application covers the chemical compounds, methods for their preparation, pharmaceutical compositions containing them, and their therapeutic applications.
Pharmaceutical companies and drug developers working on cGAS pathway inhibitors should review this filing for potential prior art concerns in related development programs. Patent applications become publicly available 18 months after their earliest priority date; this publication provides insight into the competitive landscape for cGAS-targeted therapeutics.
Archived snapshot
Apr 2, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
SOLID FORMS AND SALTS OF A QUINOLINE CGAS ANTAGONIST COMPOUND
Application US20260092048A1 Kind: A1 Apr 02, 2026
Inventors
Jian Qiu, Qi Wei, Heping Shi, Lijun Sun, Zhijian Chen
Abstract
The present disclosure provides compounds that are cGAS antagonists, solid forms of the compounds, methods of preparation of the compounds and their solid forms, pharmaceutical compositions comprising the compounds and their solid forms, and their use in medical therapy.
CPC Classifications
C07D 401/14
Filing Date
2025-09-02
Application No.
19316546
Named provisions
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