QCZ484 Phase 2 Extension Trial for Hypertensive Patients
Summary
The NIH has registered a Phase 2 open-label extension study (NCT07543120) for the drug candidate QCZ484 in hypertensive patients. The extension study is designed to collect additional safety and efficacy data from patients who successfully completed the parent study, CQCZ484A12201, or other QCZ484 studies as specified in respective parent protocols.
What changed
The NIH has registered a new Phase 2 open-label extension study (NCT07543120) for the investigational drug QCZ484 in hypertensive patients. The study will enroll patients who previously completed the parent study CQCZ484A12201 or other QCZ484 protocols. The sole intervention is QCZ484.
Pharmaceutical companies sponsoring QCZ484 development should ensure trial sites are aware of the extension protocol and enrollment criteria. Clinical investigators at participating sites should review the parent study completion requirements and verify eligibility criteria before enrolling patients in the extension.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.
Phase 2 NCT07543120 Kind: PHASE2 Apr 21, 2026
Abstract
The purpose of this extension study is to collect additional safety and efficacy on QCZ484 for hypertensive patients who successfully completed the parent study, CQCZ484A12201 or additional QCZ484 studies as specified in the respective parent study protocols.
Conditions: Hypertension (HTN)
Interventions: QCZ484
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