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QCZ484 Phase 2 Extension Trial for Hypertensive Patients

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Summary

The NIH has registered a Phase 2 open-label extension study (NCT07543120) for the drug candidate QCZ484 in hypertensive patients. The extension study is designed to collect additional safety and efficacy data from patients who successfully completed the parent study, CQCZ484A12201, or other QCZ484 studies as specified in respective parent protocols.

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What changed

The NIH has registered a new Phase 2 open-label extension study (NCT07543120) for the investigational drug QCZ484 in hypertensive patients. The study will enroll patients who previously completed the parent study CQCZ484A12201 or other QCZ484 protocols. The sole intervention is QCZ484.

Pharmaceutical companies sponsoring QCZ484 development should ensure trial sites are aware of the extension protocol and enrollment criteria. Clinical investigators at participating sites should review the parent study completion requirements and verify eligibility criteria before enrolling patients in the extension.

Archived snapshot

Apr 21, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

An Open-label Extension Safety and Efficacy Study of QCZ484 in Hypertensive Patients.

Phase 2 NCT07543120 Kind: PHASE2 Apr 21, 2026

Abstract

The purpose of this extension study is to collect additional safety and efficacy on QCZ484 for hypertensive patients who successfully completed the parent study, CQCZ484A12201 or additional QCZ484 studies as specified in the respective parent study protocols.

Conditions: Hypertension (HTN)

Interventions: QCZ484

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Last updated

Classification

Agency
NIH
Published
April 21st, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Pharmaceutical companies Clinical investigators
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Clinical trial registration Drug research
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Clinical Operations
Topics
Healthcare Public Health

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