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Propel Drug-Eluting Sinus Implant Family IBUKI Japan Cohort

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Summary

A new observational clinical trial (NCT07546682) registered on ClinicalTrials.gov on April 23, 2026, evaluating the PROPEL family of drug-eluting sinus implants for clinical safety and performance in Japanese patients with Chronic Rhinosinusitis (CRS). The study is conducted under standard of care conditions with no active interventions — purely observational. The IBUKI cohort specifically confirms product performance when used according to Instructions for Use (IFUs) in Japan.

“To confirm clinical safety and performance for the PROPEL family of products when used according to IFUs and standard of care in Japan.”

NIH , verbatim from source
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About this source

ClinicalTrials.gov is the NIH-run registry of every clinical trial conducted in the United States, plus most international trials sponsored by US-based companies or institutions. By federal law, sponsors must register Phase 2 through Phase 4 studies before enrolling patients and post results within a year of completion. This feed tracks every new trial registration and study update, around 700 a month: drug interventions, device studies, behavioral protocols, observational research. Watch this if you scout drug candidates moving into mid or late-stage development, monitor competitor pipelines, or follow rare disease research where new trials signal patient hope. GovPing parses sponsor, phase, intervention, and target indication on each entry.

What changed

This document registers a new observational clinical trial on ClinicalTrials.gov for the PROPEL family of drug-eluting sinus implants. The IBUKI Japan cohort study (NCT07546682) is designed to confirm clinical safety and performance when used according to IFUs and standard of care in Japan. The condition under study is Chronic Rhinosinusitis (CRS). There are no active interventions — the study is purely observational, following patients under standard treatment protocols.

Affected parties include sponsors conducting medical device clinical investigations in Japan and medical device manufacturers with products subject to post-market or confirmatory clinical evidence requirements. While this registration itself does not create compliance obligations, it signals continued regulatory and clinical interest in drug-eluting sinus implant technology in the Japanese market. Sponsors of similar CRS or ENT device studies should review their IFU compliance protocols given this study's stated objective of confirming use according to IFUs.

Archived snapshot

Apr 23, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Propel Drug-Eluting Sinus Implant Family IBUKI Cohort

Observational NCT07546682 Kind: OBSERVATIONAL Apr 23, 2026

Abstract

To confirm clinical safety and performance for the PROPEL family of products when used according to IFUs and standard of care in Japan.

Conditions: Chronic Rhinosinusitis (CRS)

Interventions: None, observational standard of care study

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Last updated

Classification

Agency
NIH
Published
April 23rd, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Docket
NCT07546682

Who this affects

Applies to
Medical device makers Healthcare providers
Industry sector
3345 Medical Device Manufacturing
Activity scope
Clinical trial registration Medical device evaluation Observational study
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Medical Devices Clinical Operations

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