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Pilot BA-GSH Trial for Veterans Depression at VA PC-MHI

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Summary

NIH ClinicalTrials.gov registered a pilot randomized trial (NCT07541482) evaluating Behavioral Activation-Guided Self-Help (BA-GSH) for depression among Veterans treated within the VHA Primary Care-Mental Health Integration (PC-MHI) service. The study targets the gap wherein fewer than 30% of Veterans with depressive symptoms receive psychotherapy in the VHA system, and will assess whether coached self-help delivery by diverse providers within a stepped-care model can expand access to care. Participants will be randomized to receive the BA-GSH intervention adapted for PC-MHI settings.

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What changed

The study registration documents a new pilot randomized trial of Behavioral Activation-Guided Self-Help (BA-GSH) for depression in Veterans receiving care through VHA Primary Care-Mental Health Integration (PC-MHI) services. The intervention is delivered as coached sessions accompanying a self-help program, designed to expand access beyond traditional provider-dependent psychotherapy. The trial will evaluate feasibility and preliminary efficacy within the stepped-care delivery model.

Healthcare providers, clinical investigators, and Veterans health researchers should note this trial as an implementation study evaluating a low-intensity mental health intervention within primary care settings. The design reflects growing interest in task-shifting and diverse provider models to address treatment access gaps. Results may inform future VA mental health service delivery protocols.

Archived snapshot

Apr 21, 2026

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Pilot Randomized Trial of BA-GSH in VA PC-MHI

N/A NCT07541482 Kind: NA Apr 21, 2026

Abstract

Symptoms of depression are highly prevalent among Veterans. However, fewer than 30% of individuals with these symptoms receive any psychotherapy in the Veterans Health Administration (VHA). This is due to many factors, which may include provider availability and patient preferences. Guided self-help (GSH), which involves coaching sessions with patients who are following a fully developed self-help program, has the potential to increase access to care for these Veterans, particularly if implemented within a stepped care model of mental health treatment delivery and if delivered by a diverse set of providers. The VHA's primary care-mental health integration (PCMHI) service, which focuses on short courses of care for mild to moderate symptoms, may be an ideal place in which to deploy GSH. The current project seeks conduct a pilot randomized trial of a GSH program for depression adapted for PCMHI based on behavioral activation.

Conditions: Depression

Interventions: Behavioral Activation-Guided Self-Help

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Last updated

Classification

Agency
NIH
Published
April 21st, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07541482

Who this affects

Applies to
Healthcare providers Clinical investigators Patients
Industry sector
6211 Healthcare Providers
Activity scope
Clinical trial registration Mental health treatment research Veterans healthcare services
Geographic scope
United States US

Taxonomy

Primary area
Healthcare
Operational domain
Clinical Operations
Topics
Public Health Pharmaceuticals

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