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Phase 2 Peiyuan Guben Tongluo Ointment for Elderly Sarcopenia NCT07538674

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Summary

The NIH ClinicalTrials.gov registry has published a Phase 2 clinical trial (NCT07538674) evaluating Peiyuan Guben Tongluo Ointment (Ejiao concentrated formula) for treatment of sarcopenia in elderly patients. The randomized, parallel-group study enrolls elderly sarcopenia patients and measures DXA-measured limb muscle mass increase from baseline after 12 weeks of treatment. The trial uses an agarose concentrating group as parallel control and includes exercise and nutritional intervention as co-interventions.

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What changed

This document registers a Phase 2 clinical trial on ClinicalTrials.gov, an NIH-maintained registry. The study evaluates a traditional Chinese medicine ointment (Peiyuan Guben Tongluo Ointment, Ejiao concentrated formula) in elderly patients diagnosed with sarcopenia, using DXA scans to measure limb muscle mass changes over 12 weeks. The trial design includes a parallel control arm receiving an agarose-concentrated version of the same ointment.

For pharmaceutical companies and clinical investigators, this registration provides visibility into active research in the sarcopenia therapeutic space. Sponsors developing treatments for age-related muscle loss may wish to monitor competing trial designs and endpoints. The trial does not create compliance obligations for third parties.

Archived snapshot

Apr 21, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

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Peiyuan Guben Tongluo Ointment for Elderly Sarcopenia

Phase 2 NCT07538674 Kind: PHASE2 Apr 20, 2026

Abstract

With the agarose concentrating group of Peiyuan Guben Tongluo Ointment set as the parallel control and an external control established simultaneously, this study aimed to evaluate the increases from baseline in DXA-measured limb muscle mass after 12 weeks of medication in elderly sarcopenia patients treated with the Ejiao concentrating group of Peiyuan Guben Tongluo Ointment.

Conditions: Sarcopenia in Elderly

Interventions: nutritional intervention, Exercise, Peiyuan Guben Tongluo Ointment (Ejiao concentrated), Peiyuan Guben Tongluo Ointment (Agarose concentrated)

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Last updated

Classification

Agency
NIH
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor
Document ID
NCT07538674

Who this affects

Applies to
Pharmaceutical companies Clinical investigators
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Clinical trial registration Sarcopenia treatment research
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Regulatory Affairs
Topics
Healthcare Public Health

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