Changeflow GovPing Healthcare & Life Sciences Phase 2 HNSCC Trial: Pertuzumab, Lenvatinib, Ap...
Routine Notice Added Final

Phase 2 HNSCC Trial: Pertuzumab, Lenvatinib, Apr 2026

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Summary

A single-arm, single-center Phase 2 clinical trial (NCT07550972) has been registered to evaluate the efficacy of neoadjuvant treatment with Pertuzumab combined with Lenvatinib for patients with locally advanced Squamous Cell Carcinoma of the Head and Neck (HNSCC). The trial is designated as Phase 2 with an April 2026 date. This registration provides public visibility into an active oncology research program studying a novel drug combination targeting HNSCC, a cancer with significant unmet medical need.

“Neoadjuvant Treatment of Locally Advanced HNSCC With Pertuzumab Combined With Lenvatinib”

NIH , verbatim from source
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About this source

ClinicalTrials.gov is the NIH-run registry of every clinical trial conducted in the United States, plus most international trials sponsored by US-based companies or institutions. By federal law, sponsors must register Phase 2 through Phase 4 studies before enrolling patients and post results within a year of completion. This feed tracks every new trial registration and study update, around 700 a month: drug interventions, device studies, behavioral protocols, observational research. Watch this if you scout drug candidates moving into mid or late-stage development, monitor competitor pipelines, or follow rare disease research where new trials signal patient hope. GovPing parses sponsor, phase, intervention, and target indication on each entry.

What changed

A new clinical trial registration has been published on ClinicalTrials.gov for a Phase 2 study evaluating the combination of Pertuzumab and Lenvatinib as neoadjuvant treatment for locally advanced HNSCC. The trial is registered as NCT07550972 and is described as a single-arm, single-center study assessing efficacy.

For clinical investigators and oncology research programs, this registration signals active recruitment or planning for a targeted therapy approach combining these two agents for head and neck cancer. Pharmaceutical companies with interests in these drug compounds or in HNSCC treatment development should be aware of this competing or complementary research program in the landscape.

Archived snapshot

Apr 25, 2026

GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.

← ClinicalTrials.gov Studies

Neoadjuvant Treatment of Locally Advanced HNSCC With Pertuzumab Combined With Lenvatinib.

Phase 2 NCT07550972 Kind: PHASE2 Apr 24, 2026

Abstract

A single-arm, single-center clinical trial evaluating efficacy (Phase #)

Conditions: Squamous Cell Carcinoma of the Head and Neck

Interventions: A single-arm, single-center clinical trial evaluating efficacy

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Last updated

Classification

Agency
NIH
Published
April 24th, 2026
Instrument
Notice
Branch
Executive
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Clinical investigators Healthcare providers Pharmaceutical companies
Industry sector
3254 Pharmaceutical Manufacturing
Activity scope
Clinical trials Drug research Cancer treatment
Geographic scope
United States US

Taxonomy

Primary area
Pharmaceuticals
Operational domain
Clinical Operations
Topics
Healthcare Public Health

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