USPTO Patent Grant US12583892B2: Conus Peptides for Neurodegenerative Conditions
Summary
The USPTO has granted patent US12583892B2 to Technion Research and Development Foundation Limited for modified Conantokin peptides and their use in treating neurodegenerative conditions. The patent covers specific peptide forms, nucleic acids encoding them, and compositions for modulating NMDA receptors.
What changed
USPTO patent grant US12583892B2 has been issued to Technion Research and Development Foundation Limited. The patent covers modified Conantokin peptides, nucleic acids encoding these peptides, and their application in treating neurodegenerative conditions by modulating NMDA receptors. The abstract details the invention, including chimeric polypeptides and their expression on target cell membranes.
This patent grant is a notification of intellectual property protection for a specific invention. It does not impose new regulatory obligations on regulated entities. Companies involved in pharmaceutical research and development, particularly in the areas of neurodegenerative diseases and peptide therapeutics, may find this patent relevant for competitive intelligence and freedom-to-operate analysis.
Archived snapshot
Mar 24, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Conus-based toxin peptides, nucleic acids encoding same and uses thereof in modulating NMDA receptors
Grant US12583892B2 Kind: B2 Mar 24, 2026
Assignee
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
Inventors
Shai Berlin, Ido Carmi, Shaden Zoabi
Abstract
Provided herein are modified forms of Conantokin peptides, including, modified Con-P peptides, nucleic acids encoding the same and compositions thereof. Further provided are nucleic acid molecules encoding for chimeric modified conantokin polypeptides to be expressed in or on a membrane of a target cells, compositions comprising the same and uses thereof for treating various neurodegenerative conditions.
CPC Classifications
C07K 14/435 C07K 14/43504 C07K 2319/03
Filing Date
2022-06-28
Application No.
17851430
Claims
16
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