Patent for SGLT Inhibitor Synthesis Intermediate
Summary
The USPTO has published a patent application for a crystalline form of an intermediate useful in the synthesis of SGLT inhibitors. The application details a method to improve purification efficiency and minimize related substances in the final product, potentially increasing yield.
What changed
This document is a patent application (US20260085065A1) filed by Youn Jung Yoon and Hee Kyoon Yoon with the USPTO. It describes a novel crystalline form of an intermediate for synthesizing SGLT inhibitors, aiming to resolve purification difficulties, achieve higher quality standards for related substances with fewer purification steps, and solve quality control issues in continuous synthesis processes. The application also claims an increased yield for the diphenylmethane derivative.
As this is a patent application, it does not impose direct compliance obligations on regulated entities. However, companies involved in the research, development, or manufacturing of SGLT inhibitors may find this disclosure relevant for their intellectual property strategies and process optimization efforts. The filing date was November 21, 2025.
Archived snapshot
Mar 26, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
CRYSTALLINE FORM OF SGLT INHIBITOR
Application US20260085065A1 Kind: A1 Mar 26, 2026
Inventors
Youn Jung YOON, Hee Kyoon YOON
Abstract
An intermediate useful for the synthesis of an SGLT inhibitor and a method for preparing an SGLT inhibitor are provided. By employing an intermediate having Chemical Formula 5, the difficulty of purification with existing processes can be solved, the quality requirements for related substances can be achieved with only one purification step, and the quality control problem in each step can be solved by performing several steps in situ. A method for synthesizing a compound of Chemical Formula 1 by using a compound of Chemical Formula 5 enables purification in an earlier step, thereby solving the problems of existing synthesis processes, in which the quality requirements for related substances were difficult to control step-by-step due to a continuous process, thereby minimizing the amount of related substances in the final product. In addition, the yield of a diphenylmethane derivative according to Chemical Formula 1 is increased.
CPC Classifications
C07D 407/04 C07D 307/79 C07B 2200/13
Filing Date
2025-11-21
Application No.
19396447
Named provisions
Related changes
Get daily alerts for USPTO Patent Applications - Organic Chemistry (C07D)
Daily digest delivered to your inbox.
Free. Unsubscribe anytime.
Source
About this page
Every important government, regulator, and court update from around the world. One place. Real-time. Free. Our mission
Source document text, dates, docket IDs, and authority are extracted directly from USPTO.
The summary, classification, recommended actions, deadlines, and penalty information are AI-generated from the original text and may contain errors. Always verify against the source document.
Classification
Who this affects
Taxonomy
Browse Categories
Get alerts for this source
We'll email you when USPTO Patent Applications - Organic Chemistry (C07D) publishes new changes.
Subscribed!
Optional. Filters your digest to exactly the updates that matter to you.