System to Monitor and Manage Patient Hydration via Plethysmograph Variability Index in Response to Passive Leg Raising
Summary
The USPTO published patent application US20260096773A1 on April 9, 2026, filed September 2, 2025, for a system using a processor to predict fluid responsiveness or unresponsiveness in patients based on plethysmograph variability parameters and limb-elevation fluid responsiveness parameters, then causing administration or termination of fluid delivery based on the combined prediction. The named inventors are Massi Joe E. Kiani, Bilal Muhsin, and Keith Ward Indorf. CPC classifications include A61B 5/4848 and G16H 20/17 (Health Informatics), with the application originating from US application number 19316927.
“Techniques for predicting fluid responsiveness or fluid unresponsiveness are described.”
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GovPing monitors USPTO Patent Applications - Health Informatics (G16H) for new healthcare & life sciences regulatory changes. Every update since tracking began is archived, classified, and available as free RSS or email alerts — 146 changes logged to date.
What changed
The USPTO published patent application US20260096773A1 disclosing a system for predicting fluid responsiveness in patients using two complementary prediction pathways: one based on plethysmograph variability parameters derived from plethysmograph waveforms, and another based on fluid responsiveness parameters associated with limb elevation (passive leg raising). A processor integrates these first and second predictions into an overall prediction and can trigger or halt fluid administration accordingly.
Healthcare providers and medical device manufacturers in the fluid management or monitoring space should review this application to assess whether the disclosed methods for integrating plethysmograph variability data with passive leg raising assessments may read on current or planned product lines. The patent's broad claim scope around combined prediction algorithms for fluid responsiveness could affect product development strategies for hemodynamic monitoring systems.
Archived snapshot
Apr 23, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
SYSTEM TO MONITOR AND MANAGE PATIENT HYDRATION VIA PLETHYSMOGRAPH VARIABILITY INDEX IN RESPONSE TO THE PASSIVE LEG RAISING
Application US20260096773A1 Kind: A1 Apr 09, 2026
Inventors
Massi Joe E. Kiani, Bilal Muhsin, Keith Ward Indorf
Abstract
Techniques for predicting fluid responsiveness or fluid unresponsiveness are described. A processor can determine a first prediction of fluid responsiveness or unresponsiveness based on a plethysmograph variability parameter associated with a plethysmograph waveform, and can determine a second prediction of fluid responsiveness or unresponsiveness based on a fluid responsiveness parameter that is associated with an elevation of one or more limbs of the patient. The processor can determine an overall prediction of fluid responsiveness or unresponsiveness based on the first and/or second predictions. Based on overall prediction, the processor can cause administration of fluids and/or termination of administration of fluids.
CPC Classifications
A61B 5/4848 A61B 5/02405 A61B 5/02433 A61B 5/0261 A61B 5/029 A61B 5/4839 A61B 5/4875 A61B 5/7275 A61B 5/742 G16H 20/17
Filing Date
2025-09-02
Application No.
19316927
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