Palm Olein and Palm Kernel Oil Diet Effects on Gut Hormones and Appetite
Summary
NIH ClinicalTrials.gov registered this randomized crossover study (NCT07541300) comparing postprandial effects of palm olein and palm kernel oil diets against a PUFA-rich sunflower oil diet on gut hormones and appetite in healthy adults. Participants will attend three study visits two weeks apart, providing blood samples and completing appetite questionnaires over four-hour assessment periods.
What changed
This is a clinical trial registration entry on ClinicalTrials.gov (NCT07541300) describing a randomized study investigating whether palm olein and palm kernel oil diets improve satiety and gut hormone responses compared to a PUFA-rich sunflower oil diet in healthy adults. Participants will undergo three center visits two weeks apart, providing fasting and postprandial blood samples and completing appetite questionnaires during four-hour assessment windows. The study has no compliance implications and does not create regulatory obligations for any party.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
The Effects of Palm Olein and Palm Kernel Oil Diets on Gut Hormones and Appetite in Healthy Adults
N/A NCT07541300 Kind: NA Apr 21, 2026
Abstract
The goal of this clinical trial is to investigate the postprandial effect of palm olein- and palm kernel oil- diets compared to PUFA-rich diet (sunflower oil in this study) on gut hormones response and appetite in healthy adults. The main questions it aims to answer are:
• Do palm olein- and palm kernel oil-diets postulate to improve satiety and lower appetite compared to PUFA rich diet (sunflower oil) in healthy adults? Researchers will compare diets prepared with palm olain or palm kernel oil to a diet prepared with sunflower oil to see the effects of these three diets on gut hormones and satiety score.
Participants will:
- Attend a health screening session for subjects selection according to inclusion and exclusion criteria.
- Visit the study center three times with 2 weeks apart.
- Provide blood samples and fill up questionnaires at different time point within 4 hours.
- Receive a ad libitum meal after 4 hours intervention.
Conditions: Healthy Adult
Interventions: Palm olein, Palm kernel oil, Sunflower Oil
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