Pain Neuroscience Education Versus Kinesio Tape for Carpal Tunnel Syndrome
ClinicalTrials.gov Studies
Summary
NIH ClinicalTrials.gov registered NCT07539480, a randomized controlled trial comparing Pain Neuroscience Education (PNE) versus Kinesio Tape for functional outcomes in patients with carpal tunnel syndrome. The study targets 160 participants with mild-to-moderate CTS, with an estimated completion date of April 20, 2026. This is an informational clinical trial registration with no compliance obligations.
What changed
NIH registered a new clinical trial (NCT07539480) comparing Pain Neuroscience Education to Kinesio Tape for carpal tunnel syndrome on ClinicalTrials.gov. The trial will study functional outcomes in patients with mild-to-moderate CTS. This is a standard research study registration and creates no regulatory obligations for any party.
Affected parties include research institutions and healthcare providers interested in CTS rehabilitation research. Compliance officers may note this as background on emerging conservative treatment approaches for occupational-related conditions but are not required to take any action.
Archived snapshot
Apr 21, 2026GovPing captured this document from the original source. If the source has since changed or been removed, this is the text as it existed at that time.
Pain Neuroscience Education Versus Kinesio Tape on Functional Outcomes in Patients With Carpal Tunnel Syndrome
N/A NCT07539480 Kind: NA Apr 20, 2026
Abstract
Carpal Tunnel Syndrome (CTS) is one of the most common compressive neuropathies of the upper limb, characterized by pain, numbness, and functional impairment due to median nerve compression at the wrist. Its prevalence is estimated at approximately 4.9%, with higher incidence in populations exposed to repetitive hand movements. The resulting sensory disturbances, grip weakness, and functional limitations significantly affect daily activities and quality of life.
Conservative management remains the first line of treatment for mild to moderate CTS, with therapeutic approaches traditionally including splinting, exercise therapy, nerve mobilization, and patient education. Recent interest has grown around Pain Neuroscience Education (PNE)-an educational strategy that reframes patients' understanding of pain by emphasizing the role of the central nervous system, cognitive factors, and neurophysiological processes. Studies have shown that PNE, particularly when combined with exercise or standard rehabilitation, can reduce symptom severity, improve functional outcomes, and help patients better manage chronic pain by reducing fear and catastrophizing. However, the existing literature notes that research on PNE for CTS is still limited, with some trials suggesting positive outcomes but calling for more high-quality evidence.
In parallel, Kinesio Taping (KT) has gained popularity as a noninvasive intervention believed to enhance circulation, provide proprioceptive input, and suppor...
Conditions: Carpal Tunnel Syndrome (CTS)
Interventions: group A: pain neuroscience education (PNE), group B: Patients receive Kinesio Taping
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