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PAHO Calls for Strengthened Vaccination Amid Measles Resurgence in the Americas

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Summary

PAHO called on countries in the Americas to intensify immunization efforts during Vaccination Week in the Americas (April 25 to May 2), with 21 countries planning to administer approximately 90 million vaccine doses, including catch-up vaccination for more than 7.2 million children with incomplete or zero-dose schedules. The appeal comes as measles cases in the region have already surpassed 2025 totals, with 14,767 confirmed cases across 13 countries in 2025 and over 15,300 cases reported as of April 5, 2026. The Americas eliminated measles in 2016, lost that status in 2018, regained it in 2024, and lost it again in 2025.

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PAHO, the Pan American Health Organization, issued a public health call to action urging countries in the Americas to strengthen vaccination efforts during Vaccination Week in the Americas (April 25 to May 2, 2026). The organization highlighted a sharp resurgence of measles, with confirmed cases already exceeding 2025 levels — 14,767 cases across 13 countries in 2025 and over 15,300 cases by April 5, 2026. Measles elimination status, which the region regained in 2024 after losing it in 2018, was lost again in 2025. Between 2025 and the first quarter of 2026, 43 measles-related deaths were reported in the region, with 93% of those infected unvaccinated.

Public health authorities and healthcare providers across the Americas should treat this as an indicator of erosion in routine immunization coverage. Achieving and sustaining the 95% two-dose coverage threshold is critical to measles elimination — a single case can spark an outbreak if protection levels fall below this threshold. The document signals that access barriers, low risk perception, and misinformation are the primary drivers of coverage gaps in some populations, not vaccine supply. Vaccination Week activities offer an immediate vehicle for catch-up immunization, but sustained routine programs will be essential to prevent further outbreaks.

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Apr 24, 2026

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PAHO calls to strengthen vaccination amid rising measles cases in the Americas

Vaccination Week in the Americas will support the delivery of around 90 million doses of vaccines against multiple diseases, including catch-up vaccination for more than 7.2 million children

Washington, D.C., April 23, 2026 (PAHO) – The Pan American Health Organization (PAHO) today urged countries in the region to intensify immunization efforts as part of Vaccination Week in the Americas (VWA), to be held from April 25 to May 2. The call comes amid sustained gains in vaccination coverage, which have not yet been sufficient to prevent a sharp resurgence of measles, with cases already surpassing totals recorded for all of 2025.

“The Region of the Americas has positioned itself as a global leader in immunization. We are the first region to have eliminated polio, rubella, and congenital rubella syndrome, and the only one that has recovered and improved vaccination coverage to pre-pandemic levels,” said PAHO Director Dr. Jarbas Barbosa during a press briefing in Washington.

Between 1974 and 2024, childhood vaccination in the Americas prevented an estimated 15 million deaths among children under five, more than 1.1 billion cases of disability, and nearly 28.4 billion cases of illness. However, the PAHO Director warned that “important gaps remain that we must close.”

Vaccination Week in the Americas aims to address those gaps. Since its launch in 2002, the initiative has highlighted the importance of vaccination as a cornerstone of public health and enabled the administration of more than 1.2 billion vaccine doses across the region. This year, for the first time, the regional launch will take place in Ottawa, Canada, on April 27.

In 2024, regional coverage for the measles, mumps, and rubella (MMR) vaccine reached 89% for the first dose and 79% for the second, while coverage for the third dose of the diphtheria, pertussis, and tetanus (DPT) vaccine reached 87%. Despite this progress, more than 1.4 million children did not receive a single dose of these or other vaccines. “These children are not numbers—they are lives, families, and entire communities at risk,” Barbosa stressed.

As part of this year’s activities, 21 countries plan to administer nearly 90 million doses, including more than 80 million influenza vaccines and catch-up vaccination for 7.2 million children with incomplete or zero-dose schedules.

Measles resurgence: a reversible setback

During the press briefing, the PAHO Director also raised concern about the increase in measles cases in the region. The Americas were the first region in the world to eliminate measles in 2016; this status was lost in 2018, regained in 2024, and lost again in 2025.

In 2025, 14,767 confirmed cases were reported across 13 countries—nearly 32 times more than in 2024. The trend continues in 2026: as of April 5, more than 15,300 cases have already been reported, exceeding last year’s total.

Globally, more than 250,000 measles cases were reported in 2025, over half of them in Africa, the Western Pacific Region, and Europe. Less than 6% occurred in the Americas. However, in the first three months of 2026, the region accounted for 21% of reported cases worldwide.

“The re-emergence of measles in the Americas is a significant setback, but one that is entirely reversible and demands decisive action,” Barbosa said.

He warned that measles “is not a mild disease” and can lead to serious complications such as pneumonia, encephalitis, and blindness—and even death. In 2025, around 13% of those infected required hospitalization, and 93% were unvaccinated. Between 2025 and the first quarter of 2026, 43 measles-related deaths have been reported in the region.

“The main challenge is not the availability of vaccines, but reaching those who remain unprotected in time,” he said, noting that low risk perception, misinformation, and barriers to access have contributed to declining coverage in some populations.

Because measles is highly contagious, maintaining elimination requires coverage above 95% with two doses. “A single case can spark an outbreak if we do not achieve these levels of protection,” he warned.

PAHO is supporting countries by strengthening surveillance, rapid outbreak response, and immunization planning at local level, while also facilitating equitable access to vaccines through its Revolving Funds. In 2025 alone, these mechanisms enabled the procurement of 234 million doses with savings of nearly 50%.

“Elimination is not a trophy to be stored away—it is an achievement that must be defended every day,” Barbosa said. “We have stopped measles before. We can do it again.”

He concluded by emphasizing that vaccination “is not only an individual decision—it is an act of collective solidarity,” and reiterated that the region can move toward a future where vaccine-preventable diseases no longer pose a threat to public health.

Vaccination Week in the Americas (VWA) News Releases Immunization Measles Brasil Diseases Elimination Initiative Dr. Jarbas Barbosa, PAHO/WHO Director Comprehensive Immunization (CIM)


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Last updated

Classification

Agency
PAHO
Published
April 23rd, 2026
Instrument
Notice
Branch
International
Legal weight
Non-binding
Stage
Final
Change scope
Minor

Who this affects

Applies to
Public health authorities Healthcare providers
Industry sector
9211 Government & Public Administration
Activity scope
Vaccination campaigns Disease surveillance
Geographic scope
United States US

Taxonomy

Primary area
Public Health
Operational domain
Public Health
Topics
Pharmaceuticals Healthcare

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